Emerin organizes actin flow for nuclear movement and centrosome orientation in migrating fibroblasts

In migrating fibroblasts, rearward movement of the nucleus orients the centrosome toward the leading edge. Nuclear movement results from coupling rearward-moving, dorsal actin cables to the nucleus by linear arrays of nesprin-2G and SUN2, termed transmembrane actin-associated nuclear (TAN) lines. A-...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Molecular biology of the cell 2013-12, Vol.24 (24), p.3869-3880
Hauptverfasser:	Chang, Wakam, Folker, Eric S, Worman, Howard J, Gundersen, Gregg G
Format:	Artikel
Sprache:	eng
Schlagworte:	3T3 Cells Actin Cytoskeleton - genetics Animals Cell Line Cell Movement - genetics Cell Nucleus - metabolism Cell Polarity - genetics Cell Polarity - physiology Fibroblasts Green Fluorescent Proteins - genetics Lamins - genetics Membrane Proteins - genetics Mice Nerve Tissue Proteins - genetics Nonmuscle Myosin Type IIA - genetics Nonmuscle Myosin Type IIB - genetics Nonmuscle Myosin Type IIB - metabolism Nuclear Envelope - genetics Nuclear Envelope - metabolism Nuclear Proteins - genetics RNA Interference RNA, Small Interfering Telomere-Binding Proteins - genetics
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!