Extracellular membrane vesicles from umbilical cord blood-derived MSC protect against ischemic acute kidney injury, a feature that is lost after inflammatory conditioning

Mesenchymal stromal cells (MSC) are shown to have a great therapeutic potential in many immunological disorders. Currently the therapeutic effect of MSCs is considered to be mediated via paracrine interactions with immune cells. Umbilical cord blood is an attractive but still less studied source of...

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Veröffentlicht in:	Journal of extracellular vesicles 2013-01, Vol.2 (1), p.1-n/a
Hauptverfasser:	Kilpinen, Lotta, Impola, Ulla, Sankkila, Lotta, Ritamo, Ilja, Aatonen, Maria, Kilpinen, Sami, Tuimala, Jarno, Valmu, Leena, Levijoki, Jouko, Finckenberg, Piet, Siljander, Pia, Kankuri, Esko, Mervaala, Eero, Laitinen, Saara
Format:	Artikel
Sprache:	eng
Schlagworte:	Apolipoproteins Blood & organ donations Blood platelets CD63 antigen CD81 antigen CD9 antigen Cell culture Cell growth Cell proliferation cell therapy Complement component C3 Cord blood Cytokines Electron microscopes Flow cytometry Full text Growth factors Hypoxia Immunology Immunoregulation inflammation Ischemia Kidneys Lipids Lymphocytes T Mass spectroscopy membrane trafficking Membrane vesicles Mesenchymal stem cells Molecular modelling Nanoparticles Original Paracrine signalling Penicillin Peptides Proteasomes Proteins Reperfusion Rodents Scanning electron microscopy Stem cells Stromal cells Studies Tumor necrosis factor-TNF Ultracentrifugation Umbilical cord
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