Aligned Chitosan-Polycaprolactone Polyblend Nanofibers Promote the Migration of Glioblastoma Cells

In vitro models that accurately mimic the microenvironment of invading glioblastoma multiform (GBM) cells will provide a high‐throughput system for testing potential anti‐invasion therapies. Here, the ability of chitosan‐polycaprolactone polyblend nanofibers to promote a migratory phenotype in human...

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Veröffentlicht in:	Advanced healthcare materials 2013-12, Vol.2 (12), p.1651-1659
Hauptverfasser:	Kievit, Forrest M., Cooper, Ashleigh, Jana, Soumen, Leung, Matthew C., Wang, Kui, Edmondson, Dennis, Wood, David, Lee, Jerry S. H., Ellenbogen, Richard G., Zhang, Miqin
Format:	Artikel
Sprache:	eng
Schlagworte:	Alignment cancer Cell Division - drug effects Cell Line, Tumor Cell Movement - drug effects Cell Shape - drug effects Chitosan - chemistry Chitosan - pharmacology Culture EMT Fibers Gene Expression - drug effects Glioblastoma - genetics Glioblastoma - metabolism Glioblastoma - pathology Human Humans in vitro model In vitro testing microenvironment migration nanofiber Nanofibers Nanofibers - chemistry Nanostructure Polyesters - chemistry Polyesters - pharmacology Therapy
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