Single prolonged stress impairs social and object novelty recognition in rats

•Avoidance symptoms and negative cognition in posttraumatic stress disorder (PTSD) are poorly understood.•Single prolonged stress (SPS) in rodents models characteristics of PTSD.•SPS impairs object and social novelty, which may be due to behavioral inflexibility.•Impaired recognition of familiarity...

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Veröffentlicht in:	Behavioural brain research 2013-11, Vol.256, p.591-597
Hauptverfasser:	Eagle, Andrew L., Fitzpatrick, Chris J., Perrine, Shane A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult and adolescent clinical studies Animals Anxiety disorders. Neuroses Avoidance Behavioral flexibility Biological and medical sciences Choice Behavior - physiology Disease Models, Animal Fear - physiology Fundamental and applied biological sciences. Psychology Male Medical sciences Novel object recognition Post-traumatic stress disorder Posttraumatic stress disorder Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Rats Rats, Sprague-Dawley Recognition (Psychology) - physiology Single prolonged stress Social Behavior Social choice Stress Disorders, Post-Traumatic - physiopathology Stress, Physiological - physiology Stress, Psychological - physiopathology Vertebrates: nervous system and sense organs
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