Effects of (−)-epicatechin on molecular modulators of skeletal muscle growth and differentiation

Sarcopenia is a notable and debilitating age-associated condition. Flavonoids are known for their healthy effects and limited toxicity. The flavanol (−)-epicatechin (Epi) enhances exercise capacity in mice, and Epi-rich cocoa improves skeletal muscle structure in heart failure patients. (−)-Epicatec...

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Veröffentlicht in:	The Journal of nutritional biochemistry 2014-01, Vol.25 (1), p.91-94
Hauptverfasser:	Gutierrez-Salmean, Gabriela, Ciaraldi, Theodore P., Nogueira, Leonardo, Barboza, Jonathan, Taub, Pam R., Hogan, Michael C., Henry, Robert R., Meaney, Eduardo, Villarreal, Francisco, Ceballos, Guillermo, Ramirez-Sanchez, Israel
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aging - drug effects Animals beta-Galactosidase - metabolism Cacao - chemistry Catechin - pharmacology Cell Differentiation - drug effects Epicatechin Flavonoids Follistatin - blood Hand Strength Humans Male Mice Mice, Inbred C57BL Middle Aged Muscle, Skeletal - drug effects Muscle, Skeletal - growth & development MyoD Protein - metabolism Myogenic Regulatory Factor 5 - metabolism Myogenin - metabolism Myostatin - blood Myostatin - metabolism Pilot Projects Sarcopenia Sarcopenia - drug therapy Young Adult
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