Rapid formation of multicellular spheroids in double-emulsion droplets with controllable microenvironment

An attractive option for tissue engineering is to use of multicellular spheroids as microtissues, particularly with stem cell spheroids. Conventional approaches of fabricating spheroids suffer from low throughput and polydispersity in size and fail to supplement cues from extracellular matrix (ECM)...

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Veröffentlicht in:	Scientific reports 2013-12, Vol.3 (1), p.3462-3462, Article 3462
Hauptverfasser:	Chan, Hon Fai, Zhang, Ying, Ho, Yi-Ping, Chiu, Ya-Ling, Jung, Youngmee, Leong, Kam W.
Format:	Artikel
Sprache:	eng
Schlagworte:	13/100 13/107 13/62 631/1647/277 631/532/2074 631/61/2035 631/61/54/2295 Alginic acid Arginine Aspartic acid Biomedical materials Bioreactors Cell culture Cell Culture Techniques Emulsions Emulsions - chemistry Encapsulation Extracellular Matrix Glycine Humanities and Social Sciences Humans Hydrogels Mesenchymal Stromal Cells Mesenchyme Microfluidic Analytical Techniques Microfluidics Molecular weight multidisciplinary Oil Permeability Science Spheroids Spheroids, Cellular Stem cells Tissue Engineering
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