Histoplasma yeast and mycelial transcriptomes reveal pathogenic-phase and lineage-specific gene expression profiles

The dimorphic fungus Histoplasma capsulatum causes respiratory and systemic disease in mammalian hosts by expression of factors that enable survival within phagocytic cells of the immune system. Histoplasma's dimorphism is distinguished by growth either as avirulent mycelia or as pathogenic yea...

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Veröffentlicht in:	BMC genomics 2013-10, Vol.14 (1), p.695-695, Article 695
Hauptverfasser:	Edwards, Jessica A, Chen, Chenxi, Kemski, Megan M, Hu, Jinnan, Mitchell, Thomas K, Rappleye, Chad A
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Base Sequence Cell survival Colleges & universities Gene expression Gene Expression Profiling Gene Expression Regulation, Fungal Genes, Fungal - genetics Genetic aspects Genetic research Genetic transcription Genomes Genomics Histoplasma Histoplasma - genetics Histoplasma - pathogenicity Histoplasma capsulatum Immune system Introns - genetics Mammals Messenger RNA Microbiology Models, Genetic Molecular Sequence Annotation Molecular Sequence Data Mycelium - genetics Mycelium - pathogenicity Phenotypic variations Phylogeny Physiological aspects Proteins Reproducibility of Results Reverse Transcriptase Polymerase Chain Reaction RNA Splicing - genetics Sequence Analysis, RNA Transcription, Genetic Transcriptome - genetics Virulence (Microbiology) Yeast Yeasts
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