Role of viral and host factors in interferon based therapy of hepatitis C virus infection

The current standard of care (SOC) for hepatitis C virus (HCV) infection is the combination of pegylated interferon (PEG-IFN), Ribavirin and protease inhibitor for HCV genotype 1. Nevertheless, this treatment is successful only in 70-80% of the patients. In addition, the treatment is not economical...

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Veröffentlicht in:	Virology journal 2013-10, Vol.10 (1), p.299-299, Article 299
Hauptverfasser:	Imran, Muhammad, Manzoor, Sobia, Ashraf, Javed, Khalid, Madiha, Tariq, Muqddas, Khaliq, Hafiza Madeha, Azam, Sikandar
Format:	Artikel
Sprache:	eng
Schlagworte:	Antiviral Agents - therapeutic use biomarkers Drug therapy Gene polymorphism Genes Genetic aspects Genetic Markers Genetic Variation Genomics Genotype Hepacivirus - genetics Hepatitis Hepatitis C virus Hepatitis C, Chronic - diagnosis Hepatitis C, Chronic - drug therapy Hepatitis C, Chronic - virology host-pathogen relationships Humans immune system immunomodulators Insulin resistance Interferon interferons Interferons - therapeutic use interleukins Kinases patients Prognosis proteinase inhibitors Review Ribavirin - therapeutic use single nucleotide polymorphism Single nucleotide polymorphisms Studies therapeutics Treatment Outcome
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