Variations in ncRNA gene LOC284889 and MIF-794CATT repeats are associated with malaria susceptibility in Indian populations

There are increasing evidences on the role of non-coding RNA (ncRNA) as key regulator of cellular homeostasis. LOC284889 is an uncharacterized ncRNA gene on reverse strand to MIF mapped to 22q11.23. MIF, a lymphokine, regulates innate immune response by up-regulating the expression of TLR4, suppress...

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Veröffentlicht in:	Malaria journal 2013-09, Vol.12 (1), p.345-345, Article 345
Hauptverfasser:	Jha, Aditya N, Sundaravadivel, Pandarisamy, Pati, Sudhanshu S, Patra, Pradeep K, Thangaraj, Kumarasamy
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult B cells Case-Control Studies Child Female Genes Genetic aspects Genetic Predisposition to Disease Genetic research Health aspects Humans Immune response Immune system India Intramolecular Oxidoreductases - genetics Kinases Macrophage Migration-Inhibitory Factors - genetics Malaria Malaria, Falciparum - genetics Male Medical research Medicine, Experimental Middle Aged Parasites Physiological aspects Plasmodium falciparum Polymorphism, Single Nucleotide Prevention Repetitive Sequences, Nucleic Acid Risk factors RNA, Untranslated - genetics Tumor proteins Young Adult
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