Sympathetic axonopathies and hyperinnervation in the small intestine smooth muscle of aged Fischer 344 rats

Abstract It is well documented that the intrinsic enteric nervous system of the gastrointestinal (GI) tract sustains neuronal losses and reorganizes as it ages. In contrast, age-related remodeling of the extrinsic sympathetic projections to the wall of the gut is poorly characterized. The present ex...

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