HuR regulates cyclin A and cyclin B1 mRNA stability during cell proliferation

Colorectal carcinoma RKO cells expressing reduced levels of the RNA‐binding protein HuR (ASHuR) displayed markedly reduced growth. In synchronous RKO populations, HuR was almost exclusively nuclear during early G 1 , increasing in the cytoplasm during late G 1 , S and G 2 . The expression and half‐l...

Ausführliche Beschreibung