Contribution of Protein Z and Protein Z-Dependent Protease Inhibitor in Generalized Shwartzman Reaction

OBJECTIVE:Sepsis, a leading cause of mortality in critically ill patients, is closely linked to the excessive activation of coagulation and inflammation. Protein Z, a cofactor for the protein Z-dependent protease inhibitor, enhances the inhibition of coagulation factor Xa, and protein Z-dependent pr...

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Veröffentlicht in:Critical care medicine 2013-12, Vol.41 (12), p.e447-e456
Hauptverfasser: Butschkau, Antje, Nagel, Philipp, Grambow, Eberhard, Zechner, Dietmar, Broze, George J, Vollmar, Brigitte
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Sprache:eng
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