Concise Review: Growth Differentiation Factor 15 in Pathology: A Clinical Role?

Increased blood concentration of GDF15 is associated with numerous pathological conditions, but the biological significance underlying these observations is far from clear. GDF15 seems to be an integrative signal in pathologic conditions, giving information on severity of disease, but its effectiven...

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Veröffentlicht in:	Stem cells translational medicine 2013-12, Vol.2 (12), p.946-952
Hauptverfasser:	Corre, Jill, Hébraud, Benjamin, Bourin, Philippe
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biomarkers, Tumor - metabolism Blood levels Cancer Cardiovascular Diseases - metabolism Cell growth Clinical translation Cytokines Disease Drug target Erythrocytes - metabolism Erythropoiesis Gene Expression Regulation Growth Differentiation Factor 15 - genetics Growth Differentiation Factor 15 - metabolism Growth factors Humans Malignancy Mortality Multiple myeloma Neoplasms - genetics Neoplasms - metabolism Neoplasms - pathology Pathology Prognosis Proteins Signal Transduction Tissue-Specific Progenitor and Stem Cells Tumors
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