Dopaminergic tone regulates transient potassium current maximal conductance through a translational mechanism requiring D1Rs, cAMP/PKA, Erk and mTOR

Dopamine (DA) can produce divergent effects at different time scales. DA has opposing immediate and long-term effects on the transient potassium current (IA) within neurons of the pyloric network, in the Panulirus interruptus stomatogastric ganglion. The lateral pyloric neuron (LP) expresses type 1...

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Veröffentlicht in:	BMC neuroscience 2013-11, Vol.14 (1), p.143-143, Article 143
Hauptverfasser:	Rodgers, Edmund W, Krenz, Wulf-Dieter, Jiang, Xiaoyue, Li, Lingjun, Baro, Deborah J
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antagonism Colleges & universities Crustaceans Cyclic adenylic acid Cyclic AMP - metabolism Cyclic AMP-Dependent Protein Kinases - metabolism Design of experiments Dopamine Dopamine - metabolism Extracellular Signal-Regulated MAP Kinases - physiology Ganglia, Invertebrate - physiology Kinases Mammals Membrane Potentials - physiology Neurons Neurons - metabolism Palinuridae Panulirus interruptus Patch-Clamp Techniques Physiological aspects Potassium Channels - metabolism Protein kinases Protocol Pylorus - innervation Pylorus - metabolism Receptors, Dopamine - metabolism Signal Transduction - physiology Statistical analysis TOR Serine-Threonine Kinases - metabolism
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