Pulmonary veins in the normal lung and pulmonary hypertension due to left heart disease

Despite the importance of pulmonary veins in normal lung physiology and the pathobiology of pulmonary hypertension with left heart disease (PH-LHD), pulmonary veins remain largely understudied. Difficult to identify histologically, lung venous endothelium or smooth muscle cells display no unique cha...

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Veröffentlicht in:	American journal of physiology. Lung cellular and molecular physiology 2013-11, Vol.305 (10), p.L725-L736
Hauptverfasser:	Hunt, James M, Bethea, Brian, Liu, Xiang, Gandjeva, Aneta, Mammen, Pradeep P A, Stacher, Elvira, Gandjeva, Marina R, Parish, Elisabeth, Perez, Mario, Smith, Lynelle, Graham, Brian B, Kuebler, Wolfgang M, Tuder, Rubin M
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Animals Blotting, Western Case-Control Studies Cell Proliferation Cells Child Endothelium, Vascular - metabolism Endothelium, Vascular - pathology Female Fluorescent Antibody Technique Heart Diseases - complications Heart Diseases - metabolism Heart Diseases - pathology Heart-Assist Devices Hemodynamics Humans Hypertension, Pulmonary - etiology Hypertension, Pulmonary - pathology Hypertension, Pulmonary - therapy Immunoenzyme Techniques Laser Capture Microdissection Lung - blood supply Lung - metabolism Lung - pathology Lung diseases Male Medical treatment Mice Mice, Inbred C57BL Middle Aged Prospective Studies Pulmonary arteries Pulmonary Artery - metabolism Pulmonary Artery - pathology Pulmonary Veins - metabolism Pulmonary Veins - pathology Rats Rats, Sprague-Dawley Real-Time Polymerase Chain Reaction Receptors, Urokinase Plasminogen Activator - metabolism Regression analysis Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - genetics Rodents Smooth muscle Young Adult
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