Kir6.2 limits Ca2+ overload and mitochondrial oscillations of ventricular myocytes in response to metabolic stress

ATP-sensitive K + (K ATP ) channels are abundant membrane proteins in cardiac myocytes that are directly gated by intracellular ATP and form a signaling complex with metabolic enzymes, such as creatine kinase. K ATP channels are known to be essential for adaption to cardiac stress, such as ischemia;...

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Veröffentlicht in:	American journal of physiology. Heart and circulatory physiology 2013-11, Vol.305 (10), p.H1508-H1518
Hauptverfasser:	Storey, Nina M., Stratton, Rebecca C., Rainbow, Richard D., Standen, Nicholas B., Lodwick, David
Format:	Artikel
Sprache:	eng
Schlagworte:	Signaling and Stress Response
Online-Zugang:	Volltext
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