Transmission of influenza A/H5N1 viruses in mammals

•H5N1 viruses may acquire airborne transmission through mutations in HA and PB2 and/or reassortment with human strains.•Airborne transmission requires high levels of virus replication in the upper respiratory tract of mammals.•In addition to HA-receptor specificity, HA protein stability probably aff...

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Veröffentlicht in:	Virus research 2013-12, Vol.178 (1), p.15-20
Hauptverfasser:	Imai, M., Herfst, S., Sorrell, E.M., Schrauwen, E.J.A., Linster, M., De Graaf, M., Fouchier, R.A.M., Kawaoka, Y.
Format:	Artikel
Sprache:	eng
Schlagworte:	aerosols Airborne transmission Animals Avian H5N1 influenza A virus birds droplets human influenza Humans Influenza A virus Influenza A Virus, H5N1 Subtype - genetics Influenza A Virus, H5N1 Subtype - physiology Influenza, Human - transmission Influenza, Human - virology Mammalian model Mammals - virology Orthomyxoviridae Infections - transmission Orthomyxoviridae Infections - veterinary Orthomyxoviridae Infections - virology pandemic viruses
Online-Zugang:	Volltext
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