Dopamine β-hydroxylase inhibitors enhance the discriminative stimulus effects of cocaine in rats

Inhibitors of dopamine β-hydroxylase (DBH), the enzyme that converts dopamine (DA) to norepinephrine (NE) in noradrenergic cells, have shown promise for the treatment of cocaine abuse disorders. However, the mechanisms underlying the beneficial effects of these compounds have not been fully elucidat...

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Veröffentlicht in:The Journal of pharmacology and experimental therapeutics 2013-12, Vol.347 (3), p.564-573
Hauptverfasser: Manvich, Daniel F, DePoy, Lauren M, Weinshenker, David
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Sprache:eng
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