Association of interleukin-1 gene polymorphisms with Alzheimer's disease

Interleukin‐1 (IL‐1) is markedly overexpressed in Alzheimer's disease. We found the IL‐1A 2,2 genotype in 12.9% of 232 neuropathologically confirmed Alzheimer's disease patients and 6.6% of 167 controls from four centers in the United Kingdom and United States (odds ratio, 3.0; controlled...

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Veröffentlicht in:	Annals of neurology 2000-03, Vol.47 (3), p.365-368
Hauptverfasser:	Nicoll, James A. R., Mrak, Robert E., Graham, David I., Stewart, Janice, Wilcock, Gordon, MacGowan, Sian, Esiri, Margaret M., Murray, Lilian S., Dewar, Deborah, Love, Seth, Moss, Tim, Griffin, W. Sue T.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Alleles Alzheimer Disease - genetics Biological and medical sciences Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases Genotype Humans Interleukin-1 - genetics Medical sciences Neurology Polymorphism, Genetic - genetics
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