Development of bioadhesive transdermal bupivacaine gels for enhanced local anesthetic action

Topical drug dosage forms such as ointments and creams can be easily removed through wetting, movement and contact. The new bioadhesive formulations with enhanced local anesthetic effects are needed for topical administration. The adhesive capacity of hydroxypropyl methylcellulose (HPMC) was determi...

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Veröffentlicht in:Iranian journal of pharmaceutical research : IJPR 2012-01, Vol.11 (2), p.423-431
Hauptverfasser: Cho, Cheong-Weon, Kim, Deok-Bae, Shin, Sang-Chul
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Sprache:eng
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