Mesenchymal stem cells and their use as cell replacement therapy and disease modelling tool

• Introduction • Mechanisms of immunological tolerance • MSCs and cell replacement strategies • Clinical applications based on MSCs immune modulatory properties: overview of ongoing clinical trials ‐ MSC in the HSCT setting ‐ Clinical use of MSCs in regenerative medicine to facilitate tissue r...

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Veröffentlicht in:	Journal of cellular and molecular medicine 2008-12, Vol.12 (6b), p.2552-2565
Hauptverfasser:	García‐Castro, J., Trigueros, C., Madrenas, J., Pérez‐Simón, J. A., Rodriguez, R., Menendez, P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipose tissue Animals Antigen-presenting cells Antigens Cartilage Cell differentiation Cell proliferation cell replacement therapies Clinical medicine Clinical trials Clinical Trials as Topic Cloning Cytokines differentiation Disease Fibroblasts Good Manufacturing Practice Hematopoietic stem cells Humans Immune system Immune Tolerance Immunogenicity Immunological tolerance Immunology Lymphocytes Medical research Medical treatment Mesenchymal Stem Cell Transplantation Mesenchymal stem cells Mesenchymal Stromal Cells - cytology Mesenchymal Stromal Cells - immunology Models, Biological neoplastic cell transformation Regenerative medicine Reviews Stem cell transplantation Stem cells Therapeutic applications Thymus gland
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