Enhanced and persistent levels of interleukin (IL)‐17+CD4+ T cells and serum IL‐17 in patients with early inflammatory arthritis

Summary Prognosis of patients with early inflammatory arthritis (EIA) is highly variable. The aim of this study was to compare, longitudinally and cross‐sectionally, the levels of cytokine‐expressing cells in peripheral blood (PB) from patients with EIA to those in established rheumatoid arthritis (...

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Veröffentlicht in:	Clinical and experimental immunology 2013-11, Vol.174 (2), p.292-301
Hauptverfasser:	Gullick, N. J., Abozaid, H. S., Jayaraj, D. M., Evans, H. G., Scott, D. L., Choy, E. H., Taams, L. S.
Format:	Artikel
Sprache:	eng
Schlagworte:	12-O-Tetradecanoylphorbol-13-acetate Adult Aged Antirheumatic Agents - administration & dosage Arthritis, Rheumatoid - blood Arthritis, Rheumatoid - drug therapy Arthritis, Rheumatoid - immunology Blood Proteins - immunology Blood Proteins - metabolism CD4-Positive T-Lymphocytes - drug effects CD4-Positive T-Lymphocytes - immunology Cells, Cultured Chemokine CCL3 - blood Cross-Sectional Studies Cytokines Cytokines - blood Disease Progression Drug therapy early arthritis Female Follow-Up Studies Granulocyte-Macrophage Colony-Stimulating Factor - metabolism Humans IL‐17 Interleukin-17 - blood Interleukin-17 - immunology Lymphocytes Male Medical research Middle Aged monocyte Original Th17 Th17 Cells - drug effects Th17 Cells - immunology Treatment Outcome treatment response
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