Incidence of venous thromboembolism after elective knee arthroscopic surgery: a historical cohort study

Summary Background The incidence of symptomatic venous thromboembolism (VTE) after knee arthroscopy is uncertain. Objectives To estimate the incidence of symptomatic VTE after arthroscopic knee surgery. Methods In a population‐based historical cohort study, all Olmsted County, MN, USA, residents und...

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Veröffentlicht in:Journal of thrombosis and haemostasis 2013-07, Vol.11 (7), p.1279-1286
Hauptverfasser: Mauck, K. F., Froehling, D. A., Daniels, P. R., Dahm, D. L., Ashrani, A. A., Crusan, D. J., Petterson, T. M., Bailey, K. R., Heit, J. A.
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container_end_page 1286
container_issue 7
container_start_page 1279
container_title Journal of thrombosis and haemostasis
container_volume 11
creator Mauck, K. F.
Froehling, D. A.
Daniels, P. R.
Dahm, D. L.
Ashrani, A. A.
Crusan, D. J.
Petterson, T. M.
Bailey, K. R.
Heit, J. A.
description Summary Background The incidence of symptomatic venous thromboembolism (VTE) after knee arthroscopy is uncertain. Objectives To estimate the incidence of symptomatic VTE after arthroscopic knee surgery. Methods In a population‐based historical cohort study, all Olmsted County, MN, USA, residents undergoing a first arthroscopic knee surgery during the 18‐year period of 1988–2005 were followed for incident deep venous thrombosis or pulmonary embolism. The cumulative incidence of VTE after knee arthroscopy was determined using the Kaplan–Meier product limit estimator. Patient age at surgery, sex, calendar year of surgery, body mass index, anesthesia characteristics, and hospitalization were tested as potential predictors of VTE using Cox proportional hazards modeling, both univariately and adjusted for age and sex. Results Among 4833 Olmsted County residents with knee arthroscopy, 18 developed postoperative VTE, all within the first 6 weeks after surgery. The cumulative incidence rates of symptomatic VTE at 7, 14, and 35 days were 0.2%, 0.3%, and 0.4%, respectively. The hazard for postoperative VTE was significantly increased for older patient age (hazard ratio = 1.34 for each 10‐year increase in patient age; P = 0.03) and hospitalization either before or after knee arthroscopy (hazard ratio = 14.1; P 
doi_str_mv 10.1111/jth.12283
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F. ; Froehling, D. A. ; Daniels, P. R. ; Dahm, D. L. ; Ashrani, A. A. ; Crusan, D. J. ; Petterson, T. M. ; Bailey, K. R. ; Heit, J. A.</creator><creatorcontrib>Mauck, K. F. ; Froehling, D. A. ; Daniels, P. R. ; Dahm, D. L. ; Ashrani, A. A. ; Crusan, D. J. ; Petterson, T. M. ; Bailey, K. R. ; Heit, J. A.</creatorcontrib><description>Summary Background The incidence of symptomatic venous thromboembolism (VTE) after knee arthroscopy is uncertain. Objectives To estimate the incidence of symptomatic VTE after arthroscopic knee surgery. Methods In a population‐based historical cohort study, all Olmsted County, MN, USA, residents undergoing a first arthroscopic knee surgery during the 18‐year period of 1988–2005 were followed for incident deep venous thrombosis or pulmonary embolism. The cumulative incidence of VTE after knee arthroscopy was determined using the Kaplan–Meier product limit estimator. Patient age at surgery, sex, calendar year of surgery, body mass index, anesthesia characteristics, and hospitalization were tested as potential predictors of VTE using Cox proportional hazards modeling, both univariately and adjusted for age and sex. Results Among 4833 Olmsted County residents with knee arthroscopy, 18 developed postoperative VTE, all within the first 6 weeks after surgery. The cumulative incidence rates of symptomatic VTE at 7, 14, and 35 days were 0.2%, 0.3%, and 0.4%, respectively. The hazard for postoperative VTE was significantly increased for older patient age (hazard ratio = 1.34 for each 10‐year increase in patient age; P = 0.03) and hospitalization either before or after knee arthroscopy (hazard ratio = 14.1; P &lt; 0.001). Conclusions The incidence of symptomatic VTE after arthroscopic knee surgery is very low. Older age and hospitalization are associated with increased risk. Routine prophylaxis to prevent symptomatic VTE is likely not needed in this patient population.</description><identifier>ISSN: 1538-7933</identifier><identifier>ISSN: 1538-7836</identifier><identifier>EISSN: 1538-7836</identifier><identifier>DOI: 10.1111/jth.12283</identifier><identifier>PMID: 23648016</identifier><language>eng</language><publisher>England: Elsevier Limited</publisher><subject>Adolescent ; Adult ; Age Factors ; Aged ; Aged, 80 and over ; Arthroscopy - adverse effects ; Child ; Child, Preschool ; deep venous thrombosis epidemiology ; Elective Surgical Procedures ; Female ; Hospitalization ; Humans ; Incidence ; Kaplan-Meier Estimate ; Knee Joint - surgery ; knee replacement arthroplasty ; Male ; Middle Aged ; Minnesota - epidemiology ; Proportional Hazards Models ; pulmonary embolism ; Retrospective Studies ; Risk Assessment ; Risk Factors ; Time Factors ; venous thromboembolism ; Venous Thromboembolism - epidemiology ; Venous Thromboembolism - prevention &amp; control ; Young Adult</subject><ispartof>Journal of thrombosis and haemostasis, 2013-07, Vol.11 (7), p.1279-1286</ispartof><rights>2013 International Society on Thrombosis and Haemostasis</rights><rights>2013 International Society on Thrombosis and Haemostasis.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4433-6559604834e8472d7297d669350a8e2398fa94a855161d7a0864b422ee2364b13</citedby><cites>FETCH-LOGICAL-c4433-6559604834e8472d7297d669350a8e2398fa94a855161d7a0864b422ee2364b13</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,776,780,881,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23648016$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Mauck, K. F.</creatorcontrib><creatorcontrib>Froehling, D. A.</creatorcontrib><creatorcontrib>Daniels, P. R.</creatorcontrib><creatorcontrib>Dahm, D. L.</creatorcontrib><creatorcontrib>Ashrani, A. A.</creatorcontrib><creatorcontrib>Crusan, D. J.</creatorcontrib><creatorcontrib>Petterson, T. M.</creatorcontrib><creatorcontrib>Bailey, K. R.</creatorcontrib><creatorcontrib>Heit, J. A.</creatorcontrib><title>Incidence of venous thromboembolism after elective knee arthroscopic surgery: a historical cohort study</title><title>Journal of thrombosis and haemostasis</title><addtitle>J Thromb Haemost</addtitle><description>Summary Background The incidence of symptomatic venous thromboembolism (VTE) after knee arthroscopy is uncertain. Objectives To estimate the incidence of symptomatic VTE after arthroscopic knee surgery. Methods In a population‐based historical cohort study, all Olmsted County, MN, USA, residents undergoing a first arthroscopic knee surgery during the 18‐year period of 1988–2005 were followed for incident deep venous thrombosis or pulmonary embolism. The cumulative incidence of VTE after knee arthroscopy was determined using the Kaplan–Meier product limit estimator. Patient age at surgery, sex, calendar year of surgery, body mass index, anesthesia characteristics, and hospitalization were tested as potential predictors of VTE using Cox proportional hazards modeling, both univariately and adjusted for age and sex. Results Among 4833 Olmsted County residents with knee arthroscopy, 18 developed postoperative VTE, all within the first 6 weeks after surgery. The cumulative incidence rates of symptomatic VTE at 7, 14, and 35 days were 0.2%, 0.3%, and 0.4%, respectively. The hazard for postoperative VTE was significantly increased for older patient age (hazard ratio = 1.34 for each 10‐year increase in patient age; P = 0.03) and hospitalization either before or after knee arthroscopy (hazard ratio = 14.1; P &lt; 0.001). Conclusions The incidence of symptomatic VTE after arthroscopic knee surgery is very low. Older age and hospitalization are associated with increased risk. Routine prophylaxis to prevent symptomatic VTE is likely not needed in this patient population.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Age Factors</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Arthroscopy - adverse effects</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>deep venous thrombosis epidemiology</subject><subject>Elective Surgical Procedures</subject><subject>Female</subject><subject>Hospitalization</subject><subject>Humans</subject><subject>Incidence</subject><subject>Kaplan-Meier Estimate</subject><subject>Knee Joint - surgery</subject><subject>knee replacement arthroplasty</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Minnesota - epidemiology</subject><subject>Proportional Hazards Models</subject><subject>pulmonary embolism</subject><subject>Retrospective Studies</subject><subject>Risk Assessment</subject><subject>Risk Factors</subject><subject>Time Factors</subject><subject>venous thromboembolism</subject><subject>Venous Thromboembolism - epidemiology</subject><subject>Venous Thromboembolism - prevention &amp; control</subject><subject>Young Adult</subject><issn>1538-7933</issn><issn>1538-7836</issn><issn>1538-7836</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kU1r3DAQhkVpaNKkh_6BIuilPWyib8s9FEpovgjkkp6FVh6vtbGtjSRv2X9fbTYJSSEDYgb08PLOvAh9puSYljpZ5u6YMqb5O3RAJdezSnP1_mmuOd9HH1NaEkJrycgHtM-4EppQdYAWl6PzDYwOcGjxGsYwJZy7GIZ5gPJ6nwZs2wwRQw8u-zXguxEA27ilkgsr73Ca4gLi5ge2uPMph-id7bELXYgZpzw1myO019o-wafHfoj-nP2-Pb2YXd-cX57-up45ITifKSlrRYTmArSoWFOxumqUqrkkVgPjtW5tLayWkiraVJZoJeaCMYDtSnPKD9HPne5qmg_QOBhztL1ZRT_YuDHBevP6Z_SdWYS14ZpVUssi8O1RIIb7CVI2g08O-t6OUG5jqCBEMUFZXdCv_6HLMMWxrFcoUSxLxVWhvu8oV86VIrTPZigx2_hMic88xFfYLy_dP5NPeRXgZAf89T1s3lYyV7cXO8l_vBqkyQ</recordid><startdate>201307</startdate><enddate>201307</enddate><creator>Mauck, K. 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A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Incidence of venous thromboembolism after elective knee arthroscopic surgery: a historical cohort study</atitle><jtitle>Journal of thrombosis and haemostasis</jtitle><addtitle>J Thromb Haemost</addtitle><date>2013-07</date><risdate>2013</risdate><volume>11</volume><issue>7</issue><spage>1279</spage><epage>1286</epage><pages>1279-1286</pages><issn>1538-7933</issn><issn>1538-7836</issn><eissn>1538-7836</eissn><abstract>Summary Background The incidence of symptomatic venous thromboembolism (VTE) after knee arthroscopy is uncertain. Objectives To estimate the incidence of symptomatic VTE after arthroscopic knee surgery. Methods In a population‐based historical cohort study, all Olmsted County, MN, USA, residents undergoing a first arthroscopic knee surgery during the 18‐year period of 1988–2005 were followed for incident deep venous thrombosis or pulmonary embolism. The cumulative incidence of VTE after knee arthroscopy was determined using the Kaplan–Meier product limit estimator. Patient age at surgery, sex, calendar year of surgery, body mass index, anesthesia characteristics, and hospitalization were tested as potential predictors of VTE using Cox proportional hazards modeling, both univariately and adjusted for age and sex. Results Among 4833 Olmsted County residents with knee arthroscopy, 18 developed postoperative VTE, all within the first 6 weeks after surgery. The cumulative incidence rates of symptomatic VTE at 7, 14, and 35 days were 0.2%, 0.3%, and 0.4%, respectively. The hazard for postoperative VTE was significantly increased for older patient age (hazard ratio = 1.34 for each 10‐year increase in patient age; P = 0.03) and hospitalization either before or after knee arthroscopy (hazard ratio = 14.1; P &lt; 0.001). Conclusions The incidence of symptomatic VTE after arthroscopic knee surgery is very low. Older age and hospitalization are associated with increased risk. Routine prophylaxis to prevent symptomatic VTE is likely not needed in this patient population.</abstract><cop>England</cop><pub>Elsevier Limited</pub><pmid>23648016</pmid><doi>10.1111/jth.12283</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record>
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source MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Alma/SFX Local Collection
subjects Adolescent
Adult
Age Factors
Aged
Aged, 80 and over
Arthroscopy - adverse effects
Child
Child, Preschool
deep venous thrombosis epidemiology
Elective Surgical Procedures
Female
Hospitalization
Humans
Incidence
Kaplan-Meier Estimate
Knee Joint - surgery
knee replacement arthroplasty
Male
Middle Aged
Minnesota - epidemiology
Proportional Hazards Models
pulmonary embolism
Retrospective Studies
Risk Assessment
Risk Factors
Time Factors
venous thromboembolism
Venous Thromboembolism - epidemiology
Venous Thromboembolism - prevention & control
Young Adult
title Incidence of venous thromboembolism after elective knee arthroscopic surgery: a historical cohort study
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