Lessons learned from the development of an abl tyrosine kinase inhibitor for chronic myelogenous leukemia
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Veröffentlicht in: | The Journal of clinical investigation 2000-01, Vol.105 (1), p.3-7 |
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container_title | The Journal of clinical investigation |
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creator | Druker, B J Lydon, N B |
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doi_str_mv | 10.1172/jci9083 |
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subjects | Antineoplastic Agents - therapeutic use Benzamides Binding Sites Drug Design Enzyme Inhibitors - therapeutic use Humans Imatinib Mesylate Leukemia, Myelogenous, Chronic, BCR-ABL Positive - drug therapy Piperazines - pharmacology Piperazines - therapeutic use Protein-Tyrosine Kinases - antagonists & inhibitors Proto-Oncogene Proteins c-abl - antagonists & inhibitors Proto-Oncogene Proteins c-abl - chemistry Pyrimidines - pharmacology Pyrimidines - therapeutic use |
title | Lessons learned from the development of an abl tyrosine kinase inhibitor for chronic myelogenous leukemia |
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