Postnatal isoform switch and protein localization of LEF1 and TCF7L2 transcription factors in cortical, thalamic, and mesencephalic regions of the adult mouse brain

β-Catenin signaling, leading to the activation of lymphoid enhancer-binding factor 1/T cell factor (LEF1/TCF) transcription factors, plays a well-established role in transcription regulation during development and tissue homeostasis. In the adult organism, the activity of this pathway has been found...

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Veröffentlicht in:	Brain Structure and Function 2013-11, Vol.218 (6), p.1531-1549
Hauptverfasser:	Nagalski, A., Irimia, M., Szewczyk, L., Ferran, J. L., Misztal, K., Kuznicki, J., Wisniewska, M. B.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals beta Catenin - metabolism Biomedical and Life Sciences Biomedicine Brain research Cell Biology Cerebral Cortex - metabolism Cytoplasm DNA Primers - genetics Fluorescent Antibody Technique Gene Expression Profiling Gene Expression Regulation, Developmental - genetics HeLa Cells Humans Image Processing, Computer-Assisted Immunoblotting Lymphoid Enhancer-Binding Factor 1 - genetics Lymphoid Enhancer-Binding Factor 1 - metabolism Mesencephalon - metabolism Mice Mice, Inbred C57BL Neurology Neurons Neurosciences Original Original Article Plasmids - genetics Protein Isoforms - genetics Protein Isoforms - metabolism Proteins Reverse Transcriptase Polymerase Chain Reaction Signal transduction Signal Transduction - genetics Thalamus - metabolism Transcription Factor 7-Like 2 Protein - genetics Transcription Factor 7-Like 2 Protein - metabolism
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