Characterization of a novel long noncoding RNA, SCAL1, induced by cigarette smoke and elevated in lung cancer cell lines

The incidence of lung diseases and cancer caused by cigarette smoke is increasing. The molecular mechanisms of gene regulation induced by cigarette smoke that ultimately lead to cancer remain unclear. This report describes a novel long noncoding RNA (lncRNA) that is induced by cigarette smoke extrac...

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Veröffentlicht in:	American journal of respiratory cell and molecular biology 2013-08, Vol.49 (2), p.204-211
Hauptverfasser:	Thai, Philip, Statt, Sarah, Chen, Ching Hsien, Liang, Ellen, Campbell, Caitlin, Wu, Reen
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Line, Tumor Chromosomes, Human, Pair 5 - metabolism Female Gene Expression Regulation, Neoplastic Gene Knockdown Techniques Humans Intracellular Signaling Peptides and Proteins - biosynthesis Kelch-Like ECH-Associated Protein 1 Lung Neoplasms - chemically induced Lung Neoplasms - metabolism Lung Neoplasms - pathology Male Neoplasm Proteins - biosynthesis NF-E2 Transcription Factor, p45 Subunit - biosynthesis NF-E2-Related Factor 2 - biosynthesis Oxidative Stress Rapid Communications RNA, Long Noncoding - biosynthesis RNA, Neoplasm - biosynthesis Smoking - adverse effects Smoking - metabolism Smoking - pathology
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