Endothelial cells from cord blood CD133+CD34+ progenitors share phenotypic, functional and gene expression profile similarities with lymphatics

The existence of endothelial progenitor cells (EPC) with high cell‐cycle rate in human umbilical cord blood has been recently shown and represents a challenging strategy for therapeutic neovascularization. To enhance knowledge for future cellular therapy, we compared the phenotypic, functional and g...

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Veröffentlicht in:	Journal of cellular and molecular medicine 2009-03, Vol.13 (3), p.522-534
Hauptverfasser:	Nguyen, Van Anh, Fürhapter, Christina, Obexer, Petra, Stössel, Hella, Romani, Nikolaus, Sepp, Norbert
Format:	Artikel
Sprache:	eng
Schlagworte:	AC133 Antigen Adenosine Angiogenesis Antibodies Antigens, CD - metabolism Antigens, CD34 - metabolism Blood Blood vessels Cardiovascular disease CD105 antigen CD34 antigen CD36 antigen Cell adhesion & migration Cell adhesion molecules Cell culture Cell cycle Cell Differentiation Cell Shape Cell therapy Cells, Cultured Child Child, Preschool Cord blood Cytokines DNA microarrays Down-Regulation Electron microscopy Endoglin endothelial cell differentiation Endothelial cells Endothelial Cells - cytology Endothelial Cells - metabolism Endothelial Cells - ultrastructure Endothelium Epidermal growth factor Extracellular matrix Fetal Blood - cytology Flow cytometry Gene expression Gene Expression Profiling Glycoproteins - metabolism Hematopoietic stem cells Hemopoiesis Humans Infant Infant, Newborn Intercellular adhesion molecule 1 lymphatic capillaries Lymphatic system Lymphatic Vessels - cytology Magnetic fields Male Morphology Oligonucleotide Array Sequence Analysis Penicillin Peptides - metabolism Phenotype Progenitor cells stem cells Stem Cells - cytology Stem Cells - metabolism Stem Cells - ultrastructure Tumor necrosis factor-α Umbilical cord Umbilical vein Up-Regulation Vascular endothelial growth factor Vascular endothelial growth factor receptor 2 Vascular endothelial growth factor receptors Vascularization vasculogenesis Weibel-Palade Bodies - ultrastructure
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