Metabolic profiling reveals key metabolic features of renal cell carcinoma

Recent evidence suggests that metabolic changes play a pivotal role in the biology of cancer and in particular renal cell carcinoma (RCC). Here, a global metabolite profiling approach was applied to characterize the metabolite pool of RCC and normal renal tissue. Advanced decision tree models were a...

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Veröffentlicht in:	Journal of cellular and molecular medicine 2011-01, Vol.15 (1), p.109-118
Hauptverfasser:	Catchpole, Gareth, Platzer, Alexander, Weikert, Cornelia, Kempkensteffen, Carsten, Johannsen, Manfred, Krause, Hans, Jung, Klaus, Miller, Kurt, Willmitzer, Lothar, Selbig, Joachim, Weikert, Steffen
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Amino acids Arachidonic acid Biomarkers Biomarkers, Tumor - metabolism Carcinoma, Renal Cell - metabolism Carcinoma, Renal Cell - pathology Classification Decision trees Fatty acids Female Females Glucose metabolism Glucose-1-phosphate Humans Inositol phosphate Kidney cancer Kidney Neoplasms - metabolism Kidney Neoplasms - pathology Male Mass spectroscopy Metabolic pathways Metabolism Metabolites Metabolome Metabolomics metastasis Middle Aged Phenotypes Prognosis Renal cell carcinoma Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization Tricarboxylic acid cycle Tumor Cells, Cultured Tumors Uracil Vitamin E
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