Hypoglycemic Activity and Antioxidative Stress of Extracts and Corymbiferin from Swertia bimaculata In Vitro and In Vivo

The present study was to investigate the anti-diabetic activities of Swertia bimaculata. Based on the glucose consumption of S. bimaculata extractsand different fractions (petroleum, dichloromethane, ethyl acetate, n-butanol and water extracts) in 3T3-L1 adipocyte assay, ethanol (ETH) and dichlorome...

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Veröffentlicht in:	Evidence-based complementary and alternative medicine 2013-01, Vol.2013 (2013), p.1-12
Hauptverfasser:	Min, Qiuxia, Chen, Jiachun, Liu, Zhaoxia, Chen, Cuiping, Wang, Yonglong, Zhang, Yutang, Wan, Luosheng, Yue, Yuedong, Xiao, Zuoqi
Format:	Artikel
Sprache:	eng
Schlagworte:	1-Phosphatidylinositol 3-kinase Acetic acid AKT2 protein Antioxidants Blood glucose Butanol Carbohydrate metabolism Carbohydrates Cardiovascular disease Chemistry Cholesterol Chromatography Diabetes Diabetes mellitus Dichloromethane Ethanol Ethyl acetate Glucose Glucose tolerance Hepatitis High density lipoprotein Histopathology Hyperglycemia Hypoglycemia Insulin Insulin resistance Kinases Laboratory animals Lipids Low density lipoprotein Medical research Metabolism Oxidative stress Pancreas Protein-serine/threonine kinase Proteins Rats Rodents Streptozocin Sucrose Sugar Swertia
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