Influence of the CCR-5/MIP-1 α axis in the pathogenesis of Rocio virus encephalitis in a mouse model

Rocio virus (ROCV) caused an outbreak of human encephalitis during the 1970s in Brazil and its immunopathogenesis remains poorly understood. CC-chemokine receptor 5 (CCR5) is a chemokine receptor that binds to macrophage inflammatory protein (MIP-1 α). Both molecules are associated with inflammatory...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The American journal of tropical medicine and hygiene 2013-11, Vol.89 (5), p.1013-1018
Hauptverfasser:	Chávez, Juliana H, França, Rafael F O, Oliveira, Carlo J F, de Aquino, Maria T P, Farias, Kleber J S, Machado, Paula R L, de Oliveira, Thelma F M, Yokosawa, Jonny, Soares, Edson G, da Silva, João S, da Fonseca, Benedito A L, Figueiredo, Luiz T M
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Brain - metabolism Brain - pathology Brain - virology Cell Movement Chemokine CCL3 - deficiency Chemokine CCL3 - genetics Encephalitis, Viral - metabolism Encephalitis, Viral - mortality Encephalitis, Viral - pathology Encephalitis, Viral - virology Flavivirus - physiology Flavivirus Infections - metabolism Flavivirus Infections - mortality Flavivirus Infections - pathology Flavivirus Infections - virology Gene Expression Host-Pathogen Interactions Humans Inflammation - metabolism Inflammation - mortality Inflammation - pathology Inflammation - virology Lymphocytes - metabolism Lymphocytes - pathology Lymphocytes - virology Macrophages - metabolism Macrophages - pathology Macrophages - virology Mice Mice, Inbred C57BL Mice, Knockout Protein Binding Receptors, CCR5 - deficiency Receptors, CCR5 - genetics Rocio virus Signal Transduction Survival Analysis Viral Load
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!