Genome-wide association study of type 2 diabetes in a sample from Mexico City and a meta-analysis of a Mexican-American sample from Starr County, Texas

Aims/hypothesis We report a genome-wide association study of type 2 diabetes in an admixed sample from Mexico City and describe the results of a meta-analysis of this study and another genome-wide scan in a Mexican-American sample from Starr County, TX, USA. The top signals observed in this meta-ana...

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Veröffentlicht in:	Diabetologia 2011-08, Vol.54 (8), p.2038-2046
Hauptverfasser:	Parra, E. J., Below, J. E., Krithika, S., Valladares, A., Barta, J. L., Cox, N. J., Hanis, C. L., Wacher, N., Garcia-Mena, J., Hu, P., Shriver, M. D., Kumate, J., McKeigue, P. M., Escobedo, J., Cruz, M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Biological and medical sciences Consortia Data processing Datasets Diabetes Diabetes mellitus Diabetes Mellitus, Type 2 - genetics Diabetes. Impaired glucose tolerance Endocrine pancreas. Apud cells (diseases) Endocrinopathies Etiopathogenesis. Screening. Investigations. Target tissue resistance Female Genetics Genome-Wide Association Study - methods Genomes Genomics Genotype Hispanic Americans Hispanic Americans - genetics Hospitals Human Physiology Humans Internal Medicine KCNQ1 protein Male Medical sciences Medicine Medicine & Public Health Meta-analysis Metabolic Diseases Mexican Americans - genetics Mexico Middle Aged Polymorphism, Single Nucleotide - genetics Potassium channels (voltage-gated) Replication Reviews Single-nucleotide polymorphism Texas Young Adult
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