Contribution of Substance Use Disorders on HIV Treatment Outcomes and Antiretroviral Medication Adherence Among HIV-Infected Persons Entering Jail
HIV and substance use are inextricably intertwined. One-sixth of people living with HIV/AIDS (PLWHA) transition through the correctional system annually. There is paucity of evidence on the impact of substance use disorders on HIV treatment engagement among jail detainees. We examined correlates of...
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Veröffentlicht in: | AIDS and behavior 2013-10, Vol.17 (Suppl 2), p.118-127 |
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creator | Chitsaz, Ehsan Meyer, Jaimie P. Krishnan, Archana Springer, Sandra A. Marcus, Ruthanne Zaller, Nick Jordan, Alison O. Lincoln, Thomas Flanigan, Timothy P. Porterfield, Jeff Altice, Frederick L. |
description | HIV and substance use are inextricably intertwined. One-sixth of people living with HIV/AIDS (PLWHA) transition through the correctional system annually. There is paucity of evidence on the impact of substance use disorders on HIV treatment engagement among jail detainees. We examined correlates of HIV treatment in the largest sample of PLWHA transitioning through jail in 10 US sites from 2007 to 2011. Cocaine, alcohol, cannabis, and heroin were the most commonly used substances. Drug use severity was negatively and independently correlated with three outcomes just before incarceration: (1) having an HIV care provider (AOR = 0.28; 95 % CI 0.09–0.89); (2) being prescribed antiretroviral therapy (AOR = 0.12; 95 % CI 0.04–0.35) and (3) high levels (>95 %) of antiretroviral medication adherence (AOR = 0.18; 95 % CI 0.05–0.62). Demographic, medical and psychiatric comorbidity, and social factors also contributed to poor outcomes. Evidence-based drug treatments that include multi-faceted interventions, including medication-assisted therapies, are urgently needed to effectively engage this vulnerable population. |
doi_str_mv | 10.1007/s10461-013-0506-0 |
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One-sixth of people living with HIV/AIDS (PLWHA) transition through the correctional system annually. There is paucity of evidence on the impact of substance use disorders on HIV treatment engagement among jail detainees. We examined correlates of HIV treatment in the largest sample of PLWHA transitioning through jail in 10 US sites from 2007 to 2011. Cocaine, alcohol, cannabis, and heroin were the most commonly used substances. Drug use severity was negatively and independently correlated with three outcomes just before incarceration: (1) having an HIV care provider (AOR = 0.28; 95 % CI 0.09–0.89); (2) being prescribed antiretroviral therapy (AOR = 0.12; 95 % CI 0.04–0.35) and (3) high levels (>95 %) of antiretroviral medication adherence (AOR = 0.18; 95 % CI 0.05–0.62). Demographic, medical and psychiatric comorbidity, and social factors also contributed to poor outcomes. Evidence-based drug treatments that include multi-faceted interventions, including medication-assisted therapies, are urgently needed to effectively engage this vulnerable population.</description><identifier>ISSN: 1090-7165</identifier><identifier>EISSN: 1573-3254</identifier><identifier>DOI: 10.1007/s10461-013-0506-0</identifier><identifier>PMID: 23673792</identifier><identifier>CODEN: AIBEFC</identifier><language>eng</language><publisher>Boston: Springer US</publisher><subject>Adolescent ; Adult ; Alcohol Drinking - epidemiology ; Anti-Retroviral Agents - administration & dosage ; Antiretroviral agents ; Cocaine ; Comorbidity ; Compliance ; Cross-Sectional Studies ; Drug abuse ; Female ; Health care ; Health Psychology ; Heroin ; HIV ; HIV Infections - drug therapy ; HIV Infections - epidemiology ; HIV Infections - psychology ; HIV Infections - virology ; Human immunodeficiency virus ; Humans ; Infectious Diseases ; Logistic Models ; Male ; Medication Adherence - psychology ; Medicine ; Medicine & Public Health ; Middle Aged ; Original Paper ; Prisoners ; Prisoners - psychology ; Prisoners - statistics & numerical data ; Prisons ; Public Health ; Socioeconomic Factors ; Substance Abuse, Intravenous - complications ; Substance Abuse, Intravenous - psychology ; Substance use ; Substance-Related Disorders - complications ; Substance-Related Disorders - psychology ; Treatment Outcome ; United States - epidemiology ; Young Adult</subject><ispartof>AIDS and behavior, 2013-10, Vol.17 (Suppl 2), p.118-127</ispartof><rights>Springer Science+Business Media New York 2013</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c470t-2f548287b442501702055df35391d83d2620f47003c9aa72de4c75be3422f033</citedby><cites>FETCH-LOGICAL-c470t-2f548287b442501702055df35391d83d2620f47003c9aa72de4c75be3422f033</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s10461-013-0506-0$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s10461-013-0506-0$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>230,314,780,784,885,27343,27923,27924,33773,41487,42556,51318</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23673792$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Chitsaz, Ehsan</creatorcontrib><creatorcontrib>Meyer, Jaimie P.</creatorcontrib><creatorcontrib>Krishnan, Archana</creatorcontrib><creatorcontrib>Springer, Sandra A.</creatorcontrib><creatorcontrib>Marcus, Ruthanne</creatorcontrib><creatorcontrib>Zaller, Nick</creatorcontrib><creatorcontrib>Jordan, Alison O.</creatorcontrib><creatorcontrib>Lincoln, Thomas</creatorcontrib><creatorcontrib>Flanigan, Timothy P.</creatorcontrib><creatorcontrib>Porterfield, Jeff</creatorcontrib><creatorcontrib>Altice, Frederick L.</creatorcontrib><title>Contribution of Substance Use Disorders on HIV Treatment Outcomes and Antiretroviral Medication Adherence Among HIV-Infected Persons Entering Jail</title><title>AIDS and behavior</title><addtitle>AIDS Behav</addtitle><addtitle>AIDS Behav</addtitle><description>HIV and substance use are inextricably intertwined. One-sixth of people living with HIV/AIDS (PLWHA) transition through the correctional system annually. There is paucity of evidence on the impact of substance use disorders on HIV treatment engagement among jail detainees. We examined correlates of HIV treatment in the largest sample of PLWHA transitioning through jail in 10 US sites from 2007 to 2011. Cocaine, alcohol, cannabis, and heroin were the most commonly used substances. Drug use severity was negatively and independently correlated with three outcomes just before incarceration: (1) having an HIV care provider (AOR = 0.28; 95 % CI 0.09–0.89); (2) being prescribed antiretroviral therapy (AOR = 0.12; 95 % CI 0.04–0.35) and (3) high levels (>95 %) of antiretroviral medication adherence (AOR = 0.18; 95 % CI 0.05–0.62). Demographic, medical and psychiatric comorbidity, and social factors also contributed to poor outcomes. Evidence-based drug treatments that include multi-faceted interventions, including medication-assisted therapies, are urgently needed to effectively engage this vulnerable population.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Alcohol Drinking - epidemiology</subject><subject>Anti-Retroviral Agents - administration & dosage</subject><subject>Antiretroviral agents</subject><subject>Cocaine</subject><subject>Comorbidity</subject><subject>Compliance</subject><subject>Cross-Sectional Studies</subject><subject>Drug abuse</subject><subject>Female</subject><subject>Health care</subject><subject>Health Psychology</subject><subject>Heroin</subject><subject>HIV</subject><subject>HIV Infections - drug therapy</subject><subject>HIV Infections - epidemiology</subject><subject>HIV Infections - psychology</subject><subject>HIV Infections - virology</subject><subject>Human immunodeficiency virus</subject><subject>Humans</subject><subject>Infectious 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Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Chitsaz, Ehsan</au><au>Meyer, Jaimie P.</au><au>Krishnan, Archana</au><au>Springer, Sandra A.</au><au>Marcus, Ruthanne</au><au>Zaller, Nick</au><au>Jordan, Alison O.</au><au>Lincoln, Thomas</au><au>Flanigan, Timothy P.</au><au>Porterfield, Jeff</au><au>Altice, Frederick L.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Contribution of Substance Use Disorders on HIV Treatment Outcomes and Antiretroviral Medication Adherence Among HIV-Infected Persons Entering Jail</atitle><jtitle>AIDS and behavior</jtitle><stitle>AIDS Behav</stitle><addtitle>AIDS Behav</addtitle><date>2013-10-01</date><risdate>2013</risdate><volume>17</volume><issue>Suppl 2</issue><spage>118</spage><epage>127</epage><pages>118-127</pages><issn>1090-7165</issn><eissn>1573-3254</eissn><coden>AIBEFC</coden><abstract>HIV and substance use are inextricably intertwined. One-sixth of people living with HIV/AIDS (PLWHA) transition through the correctional system annually. There is paucity of evidence on the impact of substance use disorders on HIV treatment engagement among jail detainees. We examined correlates of HIV treatment in the largest sample of PLWHA transitioning through jail in 10 US sites from 2007 to 2011. Cocaine, alcohol, cannabis, and heroin were the most commonly used substances. Drug use severity was negatively and independently correlated with three outcomes just before incarceration: (1) having an HIV care provider (AOR = 0.28; 95 % CI 0.09–0.89); (2) being prescribed antiretroviral therapy (AOR = 0.12; 95 % CI 0.04–0.35) and (3) high levels (>95 %) of antiretroviral medication adherence (AOR = 0.18; 95 % CI 0.05–0.62). Demographic, medical and psychiatric comorbidity, and social factors also contributed to poor outcomes. Evidence-based drug treatments that include multi-faceted interventions, including medication-assisted therapies, are urgently needed to effectively engage this vulnerable population.</abstract><cop>Boston</cop><pub>Springer US</pub><pmid>23673792</pmid><doi>10.1007/s10461-013-0506-0</doi><tpages>10</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Adolescent Adult Alcohol Drinking - epidemiology Anti-Retroviral Agents - administration & dosage Antiretroviral agents Cocaine Comorbidity Compliance Cross-Sectional Studies Drug abuse Female Health care Health Psychology Heroin HIV HIV Infections - drug therapy HIV Infections - epidemiology HIV Infections - psychology HIV Infections - virology Human immunodeficiency virus Humans Infectious Diseases Logistic Models Male Medication Adherence - psychology Medicine Medicine & Public Health Middle Aged Original Paper Prisoners Prisoners - psychology Prisoners - statistics & numerical data Prisons Public Health Socioeconomic Factors Substance Abuse, Intravenous - complications Substance Abuse, Intravenous - psychology Substance use Substance-Related Disorders - complications Substance-Related Disorders - psychology Treatment Outcome United States - epidemiology Young Adult |
title | Contribution of Substance Use Disorders on HIV Treatment Outcomes and Antiretroviral Medication Adherence Among HIV-Infected Persons Entering Jail |
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