Fibroblast Growth Factor-1 (FGF-1) Loaded Microbeads Enhance Local Capillary Neovascularization

Background Growth of new blood vessels (neovascularization) occurs naturally in the body, but the slow rate of the process may not be sufficient for survival of engineered tissues and transplanted cells, such as pancreatic islets. For transplanted islets, it is crucial that the transplantation site...

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Veröffentlicht in:	The Journal of surgical research 2010-05, Vol.160 (2), p.208-212
Hauptverfasser:	Moya, Monica L., B.S, Garfinkel, Marc R., M.D, Liu, Xiang, M.D, Lucas, Stephanie, Opara, Emmanuel C., Ph.D, Greisler, Howard P., M.D, Brey, Eric M., Ph.D
Format:	Artikel
Sprache:	eng
Schlagworte:	alginate Alginates Animals Biological and medical sciences Capillaries - drug effects Capillaries - physiology cellular transplant Delivery. Postpartum. Lactation FGF-1 Fibroblast Growth Factor 1 - pharmacology General aspects Glucuronic Acid Gynecology. Andrology. Obstetrics Hexuronic Acids Islets of Langerhans Transplantation - methods Medical sciences microcapsules Microspheres Models, Animal neovascularization Neovascularization, Physiologic - drug effects Omentum - blood supply Omentum - cytology protein delivery Rats Rats, Inbred Lew Surgery Tissue Engineering - methods
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