Potential Effects of Medicinal Plants and Secondary Metabolites on Acute Lung Injury
Acute lung injury (ALI) is a life-threatening syndrome that causes high morbidity and mortality worldwide. ALI is characterized by increased permeability of the alveolar-capillary membrane, edema, uncontrolled neutrophils migration to the lung, and diffuse alveolar damage, leading to acute hypoxemic...
Gespeichert in:
| Veröffentlicht in: | BioMed research international 2013-01, Vol.2013 (2013), p.1-12 |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 12 |
|---|---|
| container_issue | 2013 |
| container_start_page | 1 |
| container_title | BioMed research international |
| container_volume | 2013 |
| creator | de Paula Rogerio, Alexandre de Oliveira, Carlo Jose Freire Robison de Oliveira, Jhony Favarin, Daniely Cornélio |
| description | Acute lung injury (ALI) is a life-threatening syndrome that causes high morbidity and mortality worldwide. ALI is characterized by increased permeability of the alveolar-capillary membrane, edema, uncontrolled neutrophils migration to the lung, and diffuse alveolar damage, leading to acute hypoxemic respiratory failure. Although corticosteroids remain the mainstay of ALI treatment, they cause significant side effects. Agents of natural origin, such as medicinal plants and their secondary metabolites, mainly those with very few side effects, could be excellent alternatives for ALI treatment. Several studies, including our own, have demonstrated that plant extracts and/or secondary metabolites isolated from them reduce most ALI phenotypes in experimental animal models, including neutrophil recruitment to the lung, the production of pro-inflammatory cytokines and chemokines, edema, and vascular permeability. In this review, we summarized these studies and described the anti-inflammatory activity of various plant extracts, such as Ginkgo biloba and Punica granatum, and such secondary metabolites as epigallocatechin-3-gallate and ellagic acid. In addition, we highlight the medical potential of these extracts and plant-derived compounds for treating of ALI. |
| doi_str_mv | 10.1155/2013/576479 |
| format | Article |
| fullrecord | <record><control><sourceid>gale_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3810192</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A373373085</galeid><sourcerecordid>A373373085</sourcerecordid><originalsourceid>FETCH-LOGICAL-c565t-62f4c87f96e2854d33eaceff29c25fcad55fc8d971b54d7c11b462974baa8ef3</originalsourceid><addsrcrecordid>eNqNkc1rGzEQxUVIiU2aU-9lobcUJ6vv3UvBmCQNuDRQ34VWO7Jl1pK72k3If98JTt3kViEkMfPj8UaPkE-0vKJUymtWUn4ttRK6PiFTxqmYKSro6fHN-YRc5LwtcVVUlbU6IxMmGBNUsylZPaQB4hBsV9x4D27IRfLFD2iDCxGLD52NWLOxLX6BS7G1_TO2B9ukLgyAdCzmbhygWI5xXdzH7dg_fyQfvO0yXLze52R1e7NafJ8tf97dL-bLmZNKDjPFvHCV9rUCVknRcg7Wgfesdkx6Z1uJZ9XWmjbY1Y7SRihWa9FYW4Hn5-TbQXY_NjtoHc7R287s-7BDlybZYN53YtiYdXo0vKIlrRkKfHkV6NPvEfJgtmnscexsqBC1UoxV-h-1th2YEH1CMbcL2Zk51xx3WUmkvh4o16ece_BHH7Q0L1GZl6jMISqkP7-1fmT_BoPA5QHYBPzzp_B_aoAIePsG5qXSkv8Bewekqg</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1449662287</pqid></control><display><type>article</type><title>Potential Effects of Medicinal Plants and Secondary Metabolites on Acute Lung Injury</title><source>MEDLINE</source><source>PubMed Central Open Access</source><source>Wiley Online Library (Open Access Collection)</source><source>PubMed Central</source><source>Alma/SFX Local Collection</source><creator>de Paula Rogerio, Alexandre ; de Oliveira, Carlo Jose Freire ; Robison de Oliveira, Jhony ; Favarin, Daniely Cornélio</creator><contributor>Lemos de Andrade, Edineia</contributor><creatorcontrib>de Paula Rogerio, Alexandre ; de Oliveira, Carlo Jose Freire ; Robison de Oliveira, Jhony ; Favarin, Daniely Cornélio ; Lemos de Andrade, Edineia</creatorcontrib><description>Acute lung injury (ALI) is a life-threatening syndrome that causes high morbidity and mortality worldwide. ALI is characterized by increased permeability of the alveolar-capillary membrane, edema, uncontrolled neutrophils migration to the lung, and diffuse alveolar damage, leading to acute hypoxemic respiratory failure. Although corticosteroids remain the mainstay of ALI treatment, they cause significant side effects. Agents of natural origin, such as medicinal plants and their secondary metabolites, mainly those with very few side effects, could be excellent alternatives for ALI treatment. Several studies, including our own, have demonstrated that plant extracts and/or secondary metabolites isolated from them reduce most ALI phenotypes in experimental animal models, including neutrophil recruitment to the lung, the production of pro-inflammatory cytokines and chemokines, edema, and vascular permeability. In this review, we summarized these studies and described the anti-inflammatory activity of various plant extracts, such as Ginkgo biloba and Punica granatum, and such secondary metabolites as epigallocatechin-3-gallate and ellagic acid. In addition, we highlight the medical potential of these extracts and plant-derived compounds for treating of ALI.</description><identifier>ISSN: 2314-6133</identifier><identifier>EISSN: 2314-6141</identifier><identifier>DOI: 10.1155/2013/576479</identifier><identifier>PMID: 24224172</identifier><language>eng</language><publisher>Cairo, Egypt: Hindawi Publishing Corporation</publisher><subject>Acute Lung Injury - drug therapy ; Acute Lung Injury - pathology ; Adrenal Cortex Hormones - adverse effects ; Apoptosis ; Biomedical research ; Capillary Permeability - drug effects ; Care and treatment ; Catechin - analogs & derivatives ; Catechin - chemistry ; Catechin - therapeutic use ; Chemokines ; Cytokines ; Disease ; Ginkgo biloba - chemistry ; Ginkgo biloba - metabolism ; Health aspects ; Homeostasis ; Humans ; Ligands ; Lung - drug effects ; Lung - pathology ; Lung diseases ; Lungs ; Materia medica, Vegetable ; Medicinal plants ; Metabolites ; Mortality ; Permeability ; Plant extracts ; Plant Extracts - metabolism ; Plant Extracts - therapeutic use ; Plants, Medicinal - chemistry ; Plants, Medicinal - metabolism ; Proteins ; Respiratory distress syndrome ; Review ; Rodents ; Secondary Metabolism</subject><ispartof>BioMed research international, 2013-01, Vol.2013 (2013), p.1-12</ispartof><rights>Copyright © 2013 Daniely Cornélio Favarin et al.</rights><rights>COPYRIGHT 2013 John Wiley & Sons, Inc.</rights><rights>Copyright © 2013 Daniely Cornélio Favarin et al. Daniely Cornélio Favarin et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</rights><rights>Copyright © 2013 Daniely Cornélio Favarin et al. 2013</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c565t-62f4c87f96e2854d33eaceff29c25fcad55fc8d971b54d7c11b462974baa8ef3</citedby><cites>FETCH-LOGICAL-c565t-62f4c87f96e2854d33eaceff29c25fcad55fc8d971b54d7c11b462974baa8ef3</cites><orcidid>0000-0001-5913-3703 ; 0000-0003-2211-7333</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3810192/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3810192/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,315,728,781,785,886,27929,27930,53796,53798</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24224172$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><contributor>Lemos de Andrade, Edineia</contributor><creatorcontrib>de Paula Rogerio, Alexandre</creatorcontrib><creatorcontrib>de Oliveira, Carlo Jose Freire</creatorcontrib><creatorcontrib>Robison de Oliveira, Jhony</creatorcontrib><creatorcontrib>Favarin, Daniely Cornélio</creatorcontrib><title>Potential Effects of Medicinal Plants and Secondary Metabolites on Acute Lung Injury</title><title>BioMed research international</title><addtitle>Biomed Res Int</addtitle><description>Acute lung injury (ALI) is a life-threatening syndrome that causes high morbidity and mortality worldwide. ALI is characterized by increased permeability of the alveolar-capillary membrane, edema, uncontrolled neutrophils migration to the lung, and diffuse alveolar damage, leading to acute hypoxemic respiratory failure. Although corticosteroids remain the mainstay of ALI treatment, they cause significant side effects. Agents of natural origin, such as medicinal plants and their secondary metabolites, mainly those with very few side effects, could be excellent alternatives for ALI treatment. Several studies, including our own, have demonstrated that plant extracts and/or secondary metabolites isolated from them reduce most ALI phenotypes in experimental animal models, including neutrophil recruitment to the lung, the production of pro-inflammatory cytokines and chemokines, edema, and vascular permeability. In this review, we summarized these studies and described the anti-inflammatory activity of various plant extracts, such as Ginkgo biloba and Punica granatum, and such secondary metabolites as epigallocatechin-3-gallate and ellagic acid. In addition, we highlight the medical potential of these extracts and plant-derived compounds for treating of ALI.</description><subject>Acute Lung Injury - drug therapy</subject><subject>Acute Lung Injury - pathology</subject><subject>Adrenal Cortex Hormones - adverse effects</subject><subject>Apoptosis</subject><subject>Biomedical research</subject><subject>Capillary Permeability - drug effects</subject><subject>Care and treatment</subject><subject>Catechin - analogs & derivatives</subject><subject>Catechin - chemistry</subject><subject>Catechin - therapeutic use</subject><subject>Chemokines</subject><subject>Cytokines</subject><subject>Disease</subject><subject>Ginkgo biloba - chemistry</subject><subject>Ginkgo biloba - metabolism</subject><subject>Health aspects</subject><subject>Homeostasis</subject><subject>Humans</subject><subject>Ligands</subject><subject>Lung - drug effects</subject><subject>Lung - pathology</subject><subject>Lung diseases</subject><subject>Lungs</subject><subject>Materia medica, Vegetable</subject><subject>Medicinal plants</subject><subject>Metabolites</subject><subject>Mortality</subject><subject>Permeability</subject><subject>Plant extracts</subject><subject>Plant Extracts - metabolism</subject><subject>Plant Extracts - therapeutic use</subject><subject>Plants, Medicinal - chemistry</subject><subject>Plants, Medicinal - metabolism</subject><subject>Proteins</subject><subject>Respiratory distress syndrome</subject><subject>Review</subject><subject>Rodents</subject><subject>Secondary Metabolism</subject><issn>2314-6133</issn><issn>2314-6141</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>RHX</sourceid><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNqNkc1rGzEQxUVIiU2aU-9lobcUJ6vv3UvBmCQNuDRQ34VWO7Jl1pK72k3If98JTt3kViEkMfPj8UaPkE-0vKJUymtWUn4ttRK6PiFTxqmYKSro6fHN-YRc5LwtcVVUlbU6IxMmGBNUsylZPaQB4hBsV9x4D27IRfLFD2iDCxGLD52NWLOxLX6BS7G1_TO2B9ukLgyAdCzmbhygWI5xXdzH7dg_fyQfvO0yXLze52R1e7NafJ8tf97dL-bLmZNKDjPFvHCV9rUCVknRcg7Wgfesdkx6Z1uJZ9XWmjbY1Y7SRihWa9FYW4Hn5-TbQXY_NjtoHc7R287s-7BDlybZYN53YtiYdXo0vKIlrRkKfHkV6NPvEfJgtmnscexsqBC1UoxV-h-1th2YEH1CMbcL2Zk51xx3WUmkvh4o16ece_BHH7Q0L1GZl6jMISqkP7-1fmT_BoPA5QHYBPzzp_B_aoAIePsG5qXSkv8Bewekqg</recordid><startdate>20130101</startdate><enddate>20130101</enddate><creator>de Paula Rogerio, Alexandre</creator><creator>de Oliveira, Carlo Jose Freire</creator><creator>Robison de Oliveira, Jhony</creator><creator>Favarin, Daniely Cornélio</creator><general>Hindawi Publishing Corporation</general><general>John Wiley & Sons, Inc</general><general>Hindawi Limited</general><scope>ADJCN</scope><scope>AHFXO</scope><scope>RHU</scope><scope>RHW</scope><scope>RHX</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QL</scope><scope>7QO</scope><scope>7T7</scope><scope>7TK</scope><scope>7U7</scope><scope>7U9</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>CWDGH</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>M7P</scope><scope>P5Z</scope><scope>P62</scope><scope>P64</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0001-5913-3703</orcidid><orcidid>https://orcid.org/0000-0003-2211-7333</orcidid></search><sort><creationdate>20130101</creationdate><title>Potential Effects of Medicinal Plants and Secondary Metabolites on Acute Lung Injury</title><author>de Paula Rogerio, Alexandre ; de Oliveira, Carlo Jose Freire ; Robison de Oliveira, Jhony ; Favarin, Daniely Cornélio</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c565t-62f4c87f96e2854d33eaceff29c25fcad55fc8d971b54d7c11b462974baa8ef3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Acute Lung Injury - drug therapy</topic><topic>Acute Lung Injury - pathology</topic><topic>Adrenal Cortex Hormones - adverse effects</topic><topic>Apoptosis</topic><topic>Biomedical research</topic><topic>Capillary Permeability - drug effects</topic><topic>Care and treatment</topic><topic>Catechin - analogs & derivatives</topic><topic>Catechin - chemistry</topic><topic>Catechin - therapeutic use</topic><topic>Chemokines</topic><topic>Cytokines</topic><topic>Disease</topic><topic>Ginkgo biloba - chemistry</topic><topic>Ginkgo biloba - metabolism</topic><topic>Health aspects</topic><topic>Homeostasis</topic><topic>Humans</topic><topic>Ligands</topic><topic>Lung - drug effects</topic><topic>Lung - pathology</topic><topic>Lung diseases</topic><topic>Lungs</topic><topic>Materia medica, Vegetable</topic><topic>Medicinal plants</topic><topic>Metabolites</topic><topic>Mortality</topic><topic>Permeability</topic><topic>Plant extracts</topic><topic>Plant Extracts - metabolism</topic><topic>Plant Extracts - therapeutic use</topic><topic>Plants, Medicinal - chemistry</topic><topic>Plants, Medicinal - metabolism</topic><topic>Proteins</topic><topic>Respiratory distress syndrome</topic><topic>Review</topic><topic>Rodents</topic><topic>Secondary Metabolism</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>de Paula Rogerio, Alexandre</creatorcontrib><creatorcontrib>de Oliveira, Carlo Jose Freire</creatorcontrib><creatorcontrib>Robison de Oliveira, Jhony</creatorcontrib><creatorcontrib>Favarin, Daniely Cornélio</creatorcontrib><collection>الدوريات العلمية والإحصائية - e-Marefa Academic and Statistical Periodicals</collection><collection>معرفة - المحتوى العربي الأكاديمي المتكامل - e-Marefa Academic Complete</collection><collection>Hindawi Publishing Complete</collection><collection>Hindawi Publishing Subscription Journals</collection><collection>Hindawi Publishing Open Access</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Biotechnology Research Abstracts</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Neurosciences Abstracts</collection><collection>Toxicology Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>Advanced Technologies & Aerospace Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Technology Collection</collection><collection>Natural Science Collection (ProQuest)</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>Middle East & Africa Database</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biological Science Database</collection><collection>Advanced Technologies & Aerospace Database</collection><collection>ProQuest Advanced Technologies & Aerospace Collection</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Access via ProQuest (Open Access)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>BioMed research international</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>de Paula Rogerio, Alexandre</au><au>de Oliveira, Carlo Jose Freire</au><au>Robison de Oliveira, Jhony</au><au>Favarin, Daniely Cornélio</au><au>Lemos de Andrade, Edineia</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Potential Effects of Medicinal Plants and Secondary Metabolites on Acute Lung Injury</atitle><jtitle>BioMed research international</jtitle><addtitle>Biomed Res Int</addtitle><date>2013-01-01</date><risdate>2013</risdate><volume>2013</volume><issue>2013</issue><spage>1</spage><epage>12</epage><pages>1-12</pages><issn>2314-6133</issn><eissn>2314-6141</eissn><abstract>Acute lung injury (ALI) is a life-threatening syndrome that causes high morbidity and mortality worldwide. ALI is characterized by increased permeability of the alveolar-capillary membrane, edema, uncontrolled neutrophils migration to the lung, and diffuse alveolar damage, leading to acute hypoxemic respiratory failure. Although corticosteroids remain the mainstay of ALI treatment, they cause significant side effects. Agents of natural origin, such as medicinal plants and their secondary metabolites, mainly those with very few side effects, could be excellent alternatives for ALI treatment. Several studies, including our own, have demonstrated that plant extracts and/or secondary metabolites isolated from them reduce most ALI phenotypes in experimental animal models, including neutrophil recruitment to the lung, the production of pro-inflammatory cytokines and chemokines, edema, and vascular permeability. In this review, we summarized these studies and described the anti-inflammatory activity of various plant extracts, such as Ginkgo biloba and Punica granatum, and such secondary metabolites as epigallocatechin-3-gallate and ellagic acid. In addition, we highlight the medical potential of these extracts and plant-derived compounds for treating of ALI.</abstract><cop>Cairo, Egypt</cop><pub>Hindawi Publishing Corporation</pub><pmid>24224172</pmid><doi>10.1155/2013/576479</doi><tpages>12</tpages><orcidid>https://orcid.org/0000-0001-5913-3703</orcidid><orcidid>https://orcid.org/0000-0003-2211-7333</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 2314-6133 |
| ispartof | BioMed research international, 2013-01, Vol.2013 (2013), p.1-12 |
| issn | 2314-6133 2314-6141 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3810192 |
| source | MEDLINE; PubMed Central Open Access; Wiley Online Library (Open Access Collection); PubMed Central; Alma/SFX Local Collection |
| subjects | Acute Lung Injury - drug therapy Acute Lung Injury - pathology Adrenal Cortex Hormones - adverse effects Apoptosis Biomedical research Capillary Permeability - drug effects Care and treatment Catechin - analogs & derivatives Catechin - chemistry Catechin - therapeutic use Chemokines Cytokines Disease Ginkgo biloba - chemistry Ginkgo biloba - metabolism Health aspects Homeostasis Humans Ligands Lung - drug effects Lung - pathology Lung diseases Lungs Materia medica, Vegetable Medicinal plants Metabolites Mortality Permeability Plant extracts Plant Extracts - metabolism Plant Extracts - therapeutic use Plants, Medicinal - chemistry Plants, Medicinal - metabolism Proteins Respiratory distress syndrome Review Rodents Secondary Metabolism |
| title | Potential Effects of Medicinal Plants and Secondary Metabolites on Acute Lung Injury |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-13T11%3A49%3A26IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Potential%20Effects%20of%20Medicinal%20Plants%20and%20Secondary%20Metabolites%20on%20Acute%20Lung%20Injury&rft.jtitle=BioMed%20research%20international&rft.au=de%20Paula%20Rogerio,%20Alexandre&rft.date=2013-01-01&rft.volume=2013&rft.issue=2013&rft.spage=1&rft.epage=12&rft.pages=1-12&rft.issn=2314-6133&rft.eissn=2314-6141&rft_id=info:doi/10.1155/2013/576479&rft_dat=%3Cgale_pubme%3EA373373085%3C/gale_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1449662287&rft_id=info:pmid/24224172&rft_galeid=A373373085&rfr_iscdi=true |