Response-Guided Telaprevir Combination Treatment for Hepatitis C Virus Infection

In patients with chronic infection with HCV genotype 1 and undetectable HCV at weeks 4 and 12 of treatment, a 24-week regimen that included telaprevir, peginterferon, and ribavirin was not inferior to a 48-week regimen. Chronic infection with hepatitis C virus (HCV) represents a serious health issue...

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Veröffentlicht in:	The New England journal of medicine 2011-09, Vol.365 (11), p.1014-1024
Hauptverfasser:	Sherman, Kenneth E, Flamm, Steven L, Afdhal, Nezam H, Nelson, David R, Sulkowski, Mark S, Everson, Gregory T, Fried, Michael W, Adler, Michael, Reesink, Hendrik W, Martin, Marie, Sankoh, Abdul J, Adda, Nathalie, Kauffman, Robert S, George, Shelley, Wright, Christopher I, Poordad, Fred
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Anemia Anemia - chemically induced Antibiotics. Antiinfectious agents. Antiparasitic agents Antiretroviral drugs Antiviral agents Antiviral Agents - adverse effects Antiviral Agents - therapeutic use Antiviral drugs Biological and medical sciences Biopsy Chronic infection Drug Therapy, Combination Exanthema - chemically induced Female General aspects Genotype & phenotype Genotypes Hepacivirus - genetics Hepatitis Hepatitis C Hepatitis C - drug therapy Hepatitis C - virology Human viral diseases Humans Infections Infectious diseases Interferon Interferon-alpha - therapeutic use Male Medical sciences Middle Aged Oligopeptides - adverse effects Oligopeptides - therapeutic use Patients Pharmaceuticals Pharmacology. Drug treatments Polyethylene Glycols - therapeutic use Recombinant Proteins Ribavirin Ribavirin - therapeutic use Ribonucleic acid RNA Technical communication Viral diseases Viral hepatitis Young Adult
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