Suppressions of Serotonin-Induced Increased Vascular Permeability and Leukocyte Infiltration by Bixa orellana Leaf Extract

The aim of the present study was to evaluate the anti-inflammatory activities of aqueous extract of Bixa orellana (AEBO) leaves and its possible mechanisms in animal models. The anti-inflammatory activity of the extract was evaluated using serotonin-induced rat paw edema, increased peritoneal vascul...

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Veröffentlicht in:	BioMed research international 2013-01, Vol.2013 (2013), p.1-7
Hauptverfasser:	Ahmad, Zuraini, Zakaria, Zainul Amirudin, Ee, Gwendoline Cheng Lian, Hakim, Muhammad Nazrul, Sulaiman, NurShahira, Yong, Yoke Keong, Othman, Fauziah
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal models Animals Anti-Inflammatory Agents - administration & dosage Anti-Inflammatory Agents - chemistry Bixa orellana Bixaceae - chemistry Blood vessels Capillary Permeability - drug effects Dilleniidae Edema - chemically induced Edema - drug therapy Health aspects Leukemic Infiltration - drug therapy Leukemic Infiltration - metabolism Leukemic Infiltration - pathology Leukocytes Leukocytes - drug effects Leukocytes - metabolism Materia medica, Vegetable Nitric Oxide - metabolism Physiological aspects Plant extracts Plant Extracts - administration & dosage Plant Extracts - chemistry Plant Leaves - chemistry Rats Serotonin - pharmacology Vascular Endothelial Growth Factor A - metabolism
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