Identification of a tissue-specific, C/EBPβ-dependent pathway of differentiation for murine peritoneal macrophages

Macrophages and dendritic cells (DC) are distributed throughout the body and play important roles in pathogen detection and tissue homeostasis. In tissues, resident macrophages exhibit distinct phenotypes and activities, yet the transcriptional pathways that specify tissue-specific macrophages are l...

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Veröffentlicht in:	The Journal of immunology (1950) 2013-11, Vol.191 (9), p.4665-4675
Hauptverfasser:	Cain, Derek W, O'Koren, Emily G, Kan, Matthew J, Womble, Mandy, Sempowski, Gregory D, Hopper, Kristen, Gunn, Michael D, Kelsoe, Garnett
Format:	Artikel
Sprache:	eng
Schlagworte:	Adoptive Transfer Animals Apoptosis CCAAT-Enhancer-Binding Protein-beta - genetics CCAAT-Enhancer-Binding Protein-beta - metabolism Cell Differentiation Dendritic Cells - immunology Kidney - cytology Liver - cytology Lymph Nodes - cytology Macrophages, Alveolar - cytology Macrophages, Alveolar - immunology Macrophages, Alveolar - metabolism Macrophages, Peritoneal - cytology Macrophages, Peritoneal - immunology Macrophages, Peritoneal - metabolism Mice Mice, Inbred C57BL Mice, Knockout Phagocytosis - immunology Skin - cytology Spleen - cytology
Online-Zugang:	Volltext
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