A model of amygdala–hippocampal–prefrontal interaction in fear conditioning and extinction in animals

► We present a systems-level model of fear conditioning. ► We simulate function of the amygdala, hippocampus, and prefrontal cortex. ► The model accounts fear conditioning data, including acquisition and extinction. ► Our model also assumes that fear extinction involves inhibitory CS–no US learning....

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Veröffentlicht in:	Brain and cognition 2013-02, Vol.81 (1), p.29-43
Hauptverfasser:	Moustafa, Ahmed A., Gilbertson, Mark W., Orr, Scott P., Herzallah, Mohammad M., Servatius, Richard J., Myers, Catherine E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Affectivity. Emotion Amygdala Amygdala - physiology Anatomical correlates of behavior Animal Animals Behavioral psychophysiology Biological and medical sciences Brain Brain Hemisphere Functions Classical Conditioning Computational model Conditioning Conditioning (Psychology) - physiology Extinction Extinction, Psychological - physiology Fear Fear - physiology Fear conditioning Fundamental and applied biological sciences. Psychology Hippocampus Hippocampus - physiology Learning. Memory Models, Neurological Neural Pathways - physiology Personality. Affectivity Physiology Prediction Prefrontal Cortex - physiology Psychology. Psychoanalysis. Psychiatry Psychology. Psychophysiology Rabbits Rats Responses Stimuli Ventromedial prefrontal cortex
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