Epigenetics of Alzheimer’s Disease and Frontotemporal Dementia

This article will review the recent advances in the understanding of the role of epigenetic modifications and the promise of future epigenetic therapy in neurodegenerative dementias, including Alzheimer’s disease and frontotemporal dementia.

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Bibliographische Detailangaben
Veröffentlicht in:	Neurotherapeutics 2013-10, Vol.10 (4), p.709-721
Hauptverfasser:	Veerappan, Chendhore S., Sleiman, Sama, Coppola, Giovanni
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer Disease - genetics Alzheimer Disease - metabolism Alzheimer's disease Biomedical and Life Sciences Biomedicine Brain - metabolism Dementia Epigenesis, Genetic Epigenetics Frontotemporal Dementia - genetics Frontotemporal Dementia - metabolism Humans Nerve Degeneration - genetics Nerve Degeneration - metabolism Neurobiology Neurology Neurosciences Neurosurgery Review
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Beschreibung
Zusammenfassung:	This article will review the recent advances in the understanding of the role of epigenetic modifications and the promise of future epigenetic therapy in neurodegenerative dementias, including Alzheimer’s disease and frontotemporal dementia.
ISSN:	1933-7213 1878-7479 1878-7479
DOI:	10.1007/s13311-013-0219-0