Histone variant Htz1 promotes histone H3 acetylation to enhance nucleotide excision repair in Htz1 nucleosomes

Nucleotide excision repair (NER) is critical for maintaining genome integrity. How chromatin dynamics are regulated to facilitate this process in chromatin is still under exploration. We show here that a histone H2A variant, Htz1 (H2A.Z), in nucleosomes has a positive function in promoting efficient...

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Veröffentlicht in:	Nucleic acids research 2013-10, Vol.41 (19), p.9006-9019
Hauptverfasser:	Yu, Yachuan, Deng, Yanbo, Reed, Simon H, Millar, Catherine B, Waters, Raymond
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylation Adenosine Triphosphatases - genetics Chromatin - chemistry DNA Damage DNA Repair DNA Repair Enzymes - metabolism Gene Deletion Genome Integrity, Repair and Histone Acetyltransferases - metabolism Histones - genetics Histones - metabolism Lipoproteins - genetics Microbial Viability Nucleosomes - metabolism Pheromones - genetics Promoter Regions, Genetic Pyrimidine Dimers - metabolism Saccharomyces cerevisiae - genetics Saccharomyces cerevisiae - metabolism Saccharomyces cerevisiae Proteins - genetics Saccharomyces cerevisiae Proteins - metabolism Ultraviolet Rays
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