The Shozu Herpes Zoster (SHEZ) study: rationale, design, and description of a prospective cohort study
The incidence and risk factors for herpes zoster have been studied in cross-sectional and cohort studies, although most such studies have been conducted in Western countries. Evidence from Asian populations is limited, and no cohort study has been conducted in Asia. We are conducting a 3-year prospe...
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Veröffentlicht in: | Journal of epidemiology 2012, Vol.22 (2), p.167-174 |
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creator | Takao, Yukiko Miyazaki, Yoshiyuki Onishi, Fumitake Kumihashi, Hideaki Gomi, Yasuyuki Ishikawa, Toyokazu Okuno, Yoshinobu Mori, Yasuko Asada, Hideo Yamanishi, Koichi Iso, Hiroyasu |
description | The incidence and risk factors for herpes zoster have been studied in cross-sectional and cohort studies, although most such studies have been conducted in Western countries. Evidence from Asian populations is limited, and no cohort study has been conducted in Asia. We are conducting a 3-year prospective cohort study in Shozu County in Kagawa Prefecture, Japan to determine the incidence and predictive and immunologic factors for herpes zoster among Japanese.
The participants are followed for 3 years, and a telephone survey is conducted every 4 weeks. The participants were assigned to 1 of 3 studies. Participants in study A gave information on past history of herpes zoster and completed health questionnaires. Study B participants additionally underwent varicella-zoster virus (VZV) skin testing, and study C participants additionally underwent blood testing. If the participants develop herpes zoster, we evaluate clinical symptoms, measure cell-mediated immunity and humoral immunity using venous blood sampling, photograph skin areas with rash, conduct virus identification testing by polymerase chain reaction (PCR) and virus isolation from crust sampling, and evaluate postherpetic pain.
We recruited 12 522 participants aged 50 years or older in Shozu County from December 2009 through November 2010. The participation rate was 65.7% of the target population.
The present study is likely to provide valuable data on the incidence and predictive and immunologic factors for herpes zoster in a defined community-based population of Japanese. |
doi_str_mv | 10.2188/jea.je20110035 |
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The participants are followed for 3 years, and a telephone survey is conducted every 4 weeks. The participants were assigned to 1 of 3 studies. Participants in study A gave information on past history of herpes zoster and completed health questionnaires. Study B participants additionally underwent varicella-zoster virus (VZV) skin testing, and study C participants additionally underwent blood testing. If the participants develop herpes zoster, we evaluate clinical symptoms, measure cell-mediated immunity and humoral immunity using venous blood sampling, photograph skin areas with rash, conduct virus identification testing by polymerase chain reaction (PCR) and virus isolation from crust sampling, and evaluate postherpetic pain.
We recruited 12 522 participants aged 50 years or older in Shozu County from December 2009 through November 2010. The participation rate was 65.7% of the target population.
The present study is likely to provide valuable data on the incidence and predictive and immunologic factors for herpes zoster in a defined community-based population of Japanese.</description><identifier>ISSN: 0917-5040</identifier><identifier>EISSN: 1349-9092</identifier><identifier>DOI: 10.2188/jea.je20110035</identifier><identifier>PMID: 22343323</identifier><language>eng</language><publisher>Japan: Japan Epidemiological Association</publisher><subject>Aged ; Aged, 80 and over ; Blood ; Data processing ; Epidemiology ; Exanthema ; Female ; Follow-Up Studies ; Herpes viruses ; Herpes zoster ; Herpes Zoster - diagnosis ; Herpes Zoster - epidemiology ; Herpes Zoster - immunology ; Humans ; Immunity (cell-mediated) ; Immunity (humoral) ; Immunity, Cellular ; Immunology ; Incidence ; Inventories ; Japan - epidemiology ; Male ; Medical research ; Middle Aged ; Others ; Polymerase chain reaction ; Predictive Value of Tests ; Prospective Studies ; Research Design ; Research methodology ; Risk factors ; Sampling ; Skin Tests ; Study Profile ; Vaccines ; Varicella-zoster virus</subject><ispartof>Journal of epidemiology, 2012, Vol.22 (2), p.167-174</ispartof><rights>Copyright Japan Epidemiological Association 2012</rights><rights>2012 Japan Epidemiological Association. 2012 Japan Epidemiological Association</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c608t-afc1d39fb26e1d8650ef13c394f979c47c42d58bcc33b5422d8e70bc10f822723</citedby><cites>FETCH-LOGICAL-c608t-afc1d39fb26e1d8650ef13c394f979c47c42d58bcc33b5422d8e70bc10f822723</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3798596/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3798596/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,860,881,4009,27902,27903,27904,53769,53771</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22343323$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Takao, Yukiko</creatorcontrib><creatorcontrib>Miyazaki, Yoshiyuki</creatorcontrib><creatorcontrib>Onishi, Fumitake</creatorcontrib><creatorcontrib>Kumihashi, Hideaki</creatorcontrib><creatorcontrib>Gomi, Yasuyuki</creatorcontrib><creatorcontrib>Ishikawa, Toyokazu</creatorcontrib><creatorcontrib>Okuno, Yoshinobu</creatorcontrib><creatorcontrib>Mori, Yasuko</creatorcontrib><creatorcontrib>Asada, Hideo</creatorcontrib><creatorcontrib>Yamanishi, Koichi</creatorcontrib><creatorcontrib>Iso, Hiroyasu</creatorcontrib><creatorcontrib>SHEZ Study group</creatorcontrib><title>The Shozu Herpes Zoster (SHEZ) study: rationale, design, and description of a prospective cohort study</title><title>Journal of epidemiology</title><addtitle>J Epidemiol</addtitle><description>The incidence and risk factors for herpes zoster have been studied in cross-sectional and cohort studies, although most such studies have been conducted in Western countries. Evidence from Asian populations is limited, and no cohort study has been conducted in Asia. We are conducting a 3-year prospective cohort study in Shozu County in Kagawa Prefecture, Japan to determine the incidence and predictive and immunologic factors for herpes zoster among Japanese.
The participants are followed for 3 years, and a telephone survey is conducted every 4 weeks. The participants were assigned to 1 of 3 studies. Participants in study A gave information on past history of herpes zoster and completed health questionnaires. Study B participants additionally underwent varicella-zoster virus (VZV) skin testing, and study C participants additionally underwent blood testing. If the participants develop herpes zoster, we evaluate clinical symptoms, measure cell-mediated immunity and humoral immunity using venous blood sampling, photograph skin areas with rash, conduct virus identification testing by polymerase chain reaction (PCR) and virus isolation from crust sampling, and evaluate postherpetic pain.
We recruited 12 522 participants aged 50 years or older in Shozu County from December 2009 through November 2010. The participation rate was 65.7% of the target population.
The present study is likely to provide valuable data on the incidence and predictive and immunologic factors for herpes zoster in a defined community-based population of Japanese.</description><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Blood</subject><subject>Data processing</subject><subject>Epidemiology</subject><subject>Exanthema</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Herpes viruses</subject><subject>Herpes zoster</subject><subject>Herpes Zoster - diagnosis</subject><subject>Herpes Zoster - epidemiology</subject><subject>Herpes Zoster - immunology</subject><subject>Humans</subject><subject>Immunity (cell-mediated)</subject><subject>Immunity (humoral)</subject><subject>Immunity, Cellular</subject><subject>Immunology</subject><subject>Incidence</subject><subject>Inventories</subject><subject>Japan - epidemiology</subject><subject>Male</subject><subject>Medical research</subject><subject>Middle Aged</subject><subject>Others</subject><subject>Polymerase chain reaction</subject><subject>Predictive Value of Tests</subject><subject>Prospective Studies</subject><subject>Research Design</subject><subject>Research methodology</subject><subject>Risk factors</subject><subject>Sampling</subject><subject>Skin Tests</subject><subject>Study Profile</subject><subject>Vaccines</subject><subject>Varicella-zoster virus</subject><issn>0917-5040</issn><issn>1349-9092</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><recordid>eNpdkU1PGzEQhq2qVQm0V46V1VOQsqnt2Q-bQ6UqCg0VUg_QCxfL6x2TjTbrxd5Fgl_PhgCinDzSPPPIMy8hx5zNBZfyxwbNfIOCcc4YZB_IhEOqEsWU-EgmTPEiyVjKDshhjJuRyKVgn8mBEJACCJgQd7VGern2DwNdYegw0msfewx0erlaXp_Q2A_V_SkNpq99axqc0QpjfdPOqGmrXW1D3e161DtqaBd87ND29R1S69c-9HvDF_LJmSbi1-f3iPw7W14tVsnF39_ni18Xic2Z7BPjLK9AuVLkyCuZZwwdBwsqdapQNi1sKqpMltYClFkqRCWxYKXlzEkhCgFH5Ofe2w3lFiuLbR9Mo7tQb024197U-v9OW6_1jb_TUCiZqXwUTJ8Fwd8OGHu9raPFpjEt-iFqzkDmrAAOI_r9HbrxQxiPFLUSiqeFevLN95AdLxMDute_cKZ3CeoxQf1n-ZLgOPDt7Qav-Etk8Aj2epfP</recordid><startdate>2012</startdate><enddate>2012</enddate><creator>Takao, Yukiko</creator><creator>Miyazaki, Yoshiyuki</creator><creator>Onishi, Fumitake</creator><creator>Kumihashi, Hideaki</creator><creator>Gomi, Yasuyuki</creator><creator>Ishikawa, Toyokazu</creator><creator>Okuno, Yoshinobu</creator><creator>Mori, Yasuko</creator><creator>Asada, Hideo</creator><creator>Yamanishi, Koichi</creator><creator>Iso, Hiroyasu</creator><general>Japan Epidemiological Association</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QL</scope><scope>7QP</scope><scope>7TS</scope><scope>7U7</scope><scope>7U9</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8C1</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>BVBZV</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>H94</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>5PM</scope></search><sort><creationdate>2012</creationdate><title>The Shozu Herpes Zoster (SHEZ) study: rationale, design, and description of a prospective cohort study</title><author>Takao, Yukiko ; Miyazaki, Yoshiyuki ; Onishi, Fumitake ; Kumihashi, Hideaki ; Gomi, Yasuyuki ; Ishikawa, Toyokazu ; Okuno, Yoshinobu ; Mori, Yasuko ; Asada, Hideo ; Yamanishi, Koichi ; Iso, Hiroyasu</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c608t-afc1d39fb26e1d8650ef13c394f979c47c42d58bcc33b5422d8e70bc10f822723</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Blood</topic><topic>Data processing</topic><topic>Epidemiology</topic><topic>Exanthema</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Herpes viruses</topic><topic>Herpes zoster</topic><topic>Herpes Zoster - diagnosis</topic><topic>Herpes Zoster - epidemiology</topic><topic>Herpes Zoster - immunology</topic><topic>Humans</topic><topic>Immunity (cell-mediated)</topic><topic>Immunity (humoral)</topic><topic>Immunity, Cellular</topic><topic>Immunology</topic><topic>Incidence</topic><topic>Inventories</topic><topic>Japan - epidemiology</topic><topic>Male</topic><topic>Medical research</topic><topic>Middle Aged</topic><topic>Others</topic><topic>Polymerase chain reaction</topic><topic>Predictive Value of Tests</topic><topic>Prospective Studies</topic><topic>Research Design</topic><topic>Research methodology</topic><topic>Risk factors</topic><topic>Sampling</topic><topic>Skin Tests</topic><topic>Study Profile</topic><topic>Vaccines</topic><topic>Varicella-zoster virus</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Takao, Yukiko</creatorcontrib><creatorcontrib>Miyazaki, Yoshiyuki</creatorcontrib><creatorcontrib>Onishi, Fumitake</creatorcontrib><creatorcontrib>Kumihashi, Hideaki</creatorcontrib><creatorcontrib>Gomi, Yasuyuki</creatorcontrib><creatorcontrib>Ishikawa, Toyokazu</creatorcontrib><creatorcontrib>Okuno, Yoshinobu</creatorcontrib><creatorcontrib>Mori, Yasuko</creatorcontrib><creatorcontrib>Asada, Hideo</creatorcontrib><creatorcontrib>Yamanishi, Koichi</creatorcontrib><creatorcontrib>Iso, Hiroyasu</creatorcontrib><creatorcontrib>SHEZ Study group</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Physical Education Index</collection><collection>Toxicology Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Public Health Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>East & South Asia Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Journal of epidemiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Takao, Yukiko</au><au>Miyazaki, Yoshiyuki</au><au>Onishi, Fumitake</au><au>Kumihashi, Hideaki</au><au>Gomi, Yasuyuki</au><au>Ishikawa, Toyokazu</au><au>Okuno, Yoshinobu</au><au>Mori, Yasuko</au><au>Asada, Hideo</au><au>Yamanishi, Koichi</au><au>Iso, Hiroyasu</au><aucorp>SHEZ Study group</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The Shozu Herpes Zoster (SHEZ) study: rationale, design, and description of a prospective cohort study</atitle><jtitle>Journal of epidemiology</jtitle><addtitle>J Epidemiol</addtitle><date>2012</date><risdate>2012</risdate><volume>22</volume><issue>2</issue><spage>167</spage><epage>174</epage><pages>167-174</pages><issn>0917-5040</issn><eissn>1349-9092</eissn><abstract>The incidence and risk factors for herpes zoster have been studied in cross-sectional and cohort studies, although most such studies have been conducted in Western countries. Evidence from Asian populations is limited, and no cohort study has been conducted in Asia. We are conducting a 3-year prospective cohort study in Shozu County in Kagawa Prefecture, Japan to determine the incidence and predictive and immunologic factors for herpes zoster among Japanese.
The participants are followed for 3 years, and a telephone survey is conducted every 4 weeks. The participants were assigned to 1 of 3 studies. Participants in study A gave information on past history of herpes zoster and completed health questionnaires. Study B participants additionally underwent varicella-zoster virus (VZV) skin testing, and study C participants additionally underwent blood testing. If the participants develop herpes zoster, we evaluate clinical symptoms, measure cell-mediated immunity and humoral immunity using venous blood sampling, photograph skin areas with rash, conduct virus identification testing by polymerase chain reaction (PCR) and virus isolation from crust sampling, and evaluate postherpetic pain.
We recruited 12 522 participants aged 50 years or older in Shozu County from December 2009 through November 2010. The participation rate was 65.7% of the target population.
The present study is likely to provide valuable data on the incidence and predictive and immunologic factors for herpes zoster in a defined community-based population of Japanese.</abstract><cop>Japan</cop><pub>Japan Epidemiological Association</pub><pmid>22343323</pmid><doi>10.2188/jea.je20110035</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Aged Aged, 80 and over Blood Data processing Epidemiology Exanthema Female Follow-Up Studies Herpes viruses Herpes zoster Herpes Zoster - diagnosis Herpes Zoster - epidemiology Herpes Zoster - immunology Humans Immunity (cell-mediated) Immunity (humoral) Immunity, Cellular Immunology Incidence Inventories Japan - epidemiology Male Medical research Middle Aged Others Polymerase chain reaction Predictive Value of Tests Prospective Studies Research Design Research methodology Risk factors Sampling Skin Tests Study Profile Vaccines Varicella-zoster virus |
title | The Shozu Herpes Zoster (SHEZ) study: rationale, design, and description of a prospective cohort study |
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