Are Apathy and Depression Independently Associated with Longitudinal Trajectories of Cortical Atrophy in Mild Cognitive Impairment?

Objectives To examine whether depression and apathy are independently associated with longitudinal trajectories of cortical atrophy in the entorhinal cortex compared with frontal subregions previously implicated in late-life mood disturbance. Methods Data from 334 participants classified as having m...

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Veröffentlicht in:	The American journal of geriatric psychiatry 2013-11, Vol.21 (11), p.1098-1106
Hauptverfasser:	Zahodne, Laura B., Ph.D, Gongvatana, Assawin, Ph.D, Cohen, Ronald A., Ph.D, Ott, Brian R., M.D, Tremont, Geoffrey, Ph.D
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Aging - pathology Aging - psychology Alzheimer disease Apathy Atrophy - complications Atrophy - pathology Cerebral Cortex - pathology Cognitive Dysfunction - complications Cognitive Dysfunction - pathology Cognitive Dysfunction - psychology depression Depression - complications Depression - pathology Depression - psychology Disease Progression Female Humans Internal Medicine Male Middle Aged mild cognitive impairment Models, Psychological MRI Neuroimaging Neuropsychological Tests
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