In Vivo Whole Animal Fluorescence Imaging of a Microparticle-Based Oral Vaccine Containing (CuInSe x S2–x )/ZnS Core/Shell Quantum Dots
Zinc sulfide-coated copper indium sulfur selenide (CuInSe x S2–x /ZnS core/shell) nanocrystals were synthesized with size-tunable red to near-infrared (NIR) fluorescence with high quantum yield (40%) in water. These nanocrystals were tested as an imaging agent to track a microparticle-based oral vac...
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| Veröffentlicht in: | Nano letters 2013-09, Vol.13 (9), p.4294-4298 |
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| container_end_page | 4298 |
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| container_issue | 9 |
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| container_title | Nano letters |
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| creator | Panthani, Matthew G Khan, Tarik A Reid, Dariya K Hellebusch, Daniel J Rasch, Michael R Maynard, Jennifer A Korgel, Brian A |
| description | Zinc sulfide-coated copper indium sulfur selenide (CuInSe x S2–x /ZnS core/shell) nanocrystals were synthesized with size-tunable red to near-infrared (NIR) fluorescence with high quantum yield (40%) in water. These nanocrystals were tested as an imaging agent to track a microparticle-based oral vaccine administered to mice. Poly(lactic-co-glycolic acid) (PLGA) microparticle-encapsulated CuInSe x Se2–x /ZnS quantum dots were orally administered to mice and were found to provide a distinct visible fluorescent marker in the gastrointestinal tract of living mice. |
| doi_str_mv | 10.1021/nl402054w |
| format | Article |
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These nanocrystals were tested as an imaging agent to track a microparticle-based oral vaccine administered to mice. Poly(lactic-co-glycolic acid) (PLGA) microparticle-encapsulated CuInSe x Se2–x /ZnS quantum dots were orally administered to mice and were found to provide a distinct visible fluorescent marker in the gastrointestinal tract of living mice.</description><identifier>ISSN: 1530-6984</identifier><identifier>EISSN: 1530-6992</identifier><identifier>DOI: 10.1021/nl402054w</identifier><identifier>PMID: 23915166</identifier><language>eng</language><publisher>Washington, DC: American Chemical Society</publisher><subject>Applied sciences ; Condensed matter: electronic structure, electrical, magnetic, and optical properties ; Cross-disciplinary physics: materials science; rheology ; Electronics ; Exact sciences and technology ; Fullerenes and related materials ; Infrared and raman spectra and scattering ; Materials science ; Molecular electronics, nanoelectronics ; Nanocrystalline materials ; Nanoscale materials and structures: fabrication and characterization ; Optical properties and condensed-matter spectroscopy and other interactions of matter with particles and radiation ; Physics ; Quantum dots ; Semiconductor electronics. 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These nanocrystals were tested as an imaging agent to track a microparticle-based oral vaccine administered to mice. Poly(lactic-co-glycolic acid) (PLGA) microparticle-encapsulated CuInSe x Se2–x /ZnS quantum dots were orally administered to mice and were found to provide a distinct visible fluorescent marker in the gastrointestinal tract of living mice.</description><subject>Applied sciences</subject><subject>Condensed matter: electronic structure, electrical, magnetic, and optical properties</subject><subject>Cross-disciplinary physics: materials science; rheology</subject><subject>Electronics</subject><subject>Exact sciences and technology</subject><subject>Fullerenes and related materials</subject><subject>Infrared and raman spectra and scattering</subject><subject>Materials science</subject><subject>Molecular electronics, nanoelectronics</subject><subject>Nanocrystalline materials</subject><subject>Nanoscale materials and structures: fabrication and characterization</subject><subject>Optical properties and condensed-matter spectroscopy and other interactions of matter with particles and radiation</subject><subject>Physics</subject><subject>Quantum dots</subject><subject>Semiconductor electronics. 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Solid state devices</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Panthani, Matthew G</creatorcontrib><creatorcontrib>Khan, Tarik A</creatorcontrib><creatorcontrib>Reid, Dariya K</creatorcontrib><creatorcontrib>Hellebusch, Daniel J</creatorcontrib><creatorcontrib>Rasch, Michael R</creatorcontrib><creatorcontrib>Maynard, Jennifer A</creatorcontrib><creatorcontrib>Korgel, Brian A</creatorcontrib><collection>Pascal-Francis</collection><collection>CrossRef</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Nano letters</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Panthani, Matthew G</au><au>Khan, Tarik A</au><au>Reid, Dariya K</au><au>Hellebusch, Daniel J</au><au>Rasch, Michael R</au><au>Maynard, Jennifer A</au><au>Korgel, Brian A</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>In Vivo Whole Animal Fluorescence Imaging of a Microparticle-Based Oral Vaccine Containing (CuInSe x S2–x )/ZnS Core/Shell Quantum Dots</atitle><jtitle>Nano letters</jtitle><addtitle>Nano Lett</addtitle><date>2013-09-11</date><risdate>2013</risdate><volume>13</volume><issue>9</issue><spage>4294</spage><epage>4298</epage><pages>4294-4298</pages><issn>1530-6984</issn><eissn>1530-6992</eissn><abstract>Zinc sulfide-coated copper indium sulfur selenide (CuInSe x S2–x /ZnS core/shell) nanocrystals were synthesized with size-tunable red to near-infrared (NIR) fluorescence with high quantum yield (40%) in water. 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| fulltext | fulltext |
| identifier | ISSN: 1530-6984 |
| ispartof | Nano letters, 2013-09, Vol.13 (9), p.4294-4298 |
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| language | eng |
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| source | American Chemical Society Journals |
| subjects | Applied sciences Condensed matter: electronic structure, electrical, magnetic, and optical properties Cross-disciplinary physics: materials science rheology Electronics Exact sciences and technology Fullerenes and related materials Infrared and raman spectra and scattering Materials science Molecular electronics, nanoelectronics Nanocrystalline materials Nanoscale materials and structures: fabrication and characterization Optical properties and condensed-matter spectroscopy and other interactions of matter with particles and radiation Physics Quantum dots Semiconductor electronics. Microelectronics. Optoelectronics. Solid state devices |
| title | In Vivo Whole Animal Fluorescence Imaging of a Microparticle-Based Oral Vaccine Containing (CuInSe x S2–x )/ZnS Core/Shell Quantum Dots |
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