Eukaryotic Release Factor 3 Is Required for Multiple Turnovers of Peptide Release Catalysis by Eukaryotic Release Factor 1

Eukaryotic peptide release factor 3 (eRF3) is a conserved, essential gene in eukaryotes implicated in translation termination. We have systematically measured the contribution of eRF3 to the rates of peptide release with both saturating and limiting levels of eukaryotic release factor 1 (eRF1). Alth...

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Veröffentlicht in:	The Journal of biological chemistry 2013-10, Vol.288 (41), p.29530-29538
Hauptverfasser:	Eyler, Daniel E., Wehner, Karen A., Green, Rachel
Format:	Artikel
Sprache:	eng
Schlagworte:	Blotting, Western Catalysis Codon, Terminator - genetics Guanosine Triphosphate - metabolism Kinetics Models, Genetic Mutation Peptide Chain Termination, Translational - genetics Peptide Termination Factors - genetics Peptide Termination Factors - metabolism Peptides - genetics Peptides - metabolism Polyribosomes - genetics Polyribosomes - metabolism Protein Binding Protein Biosynthesis - genetics Protein Synthesis Protein Synthesis and Degradation Ribosomes Ribosomes - genetics Ribosomes - metabolism Saccharomyces cerevisiae - genetics Saccharomyces cerevisiae - metabolism Saccharomyces cerevisiae Proteins - genetics Saccharomyces cerevisiae Proteins - metabolism Translation Translation Control Translation Release Factors Translational Control
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