Effect of Dynamic DNA Methylation and Histone Acetylation on cPouV Expression in Differentiation of Chick Embryonic Germ Cells

As a crucial pluripotency-related factor, the epigenetic regulation of Oct4 has been studied intensively in mammalians. However, its dynamic changes of DNA methylation and histone modification in avians remain poorly understood. In the present study, we first described the alterations of DNA methyla...

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Veröffentlicht in:	Stem cells and development 2013-10, Vol.22 (20), p.2725-2735
Hauptverfasser:	Jiao, Fei, Wang, Xin, Yan, Zhonghai, Liu, Changfu, Yue, Zhen, Li, Zunling, Ma, Ying, Li, Youjie, Wang, Juan
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylation Animals Avian Proteins - genetics Avian Proteins - metabolism Cell Differentiation Chick Embryo Chickens - genetics Chickens - metabolism Deoxycytidine - pharmacology DNA (Cytosine-5-)-Methyltransferases - genetics DNA (Cytosine-5-)-Methyltransferases - metabolism DNA Methylation - drug effects Embryonic Stem Cells - cytology Embryonic Stem Cells - drug effects Embryonic Stem Cells - metabolism Epigenesis, Genetic Gene Expression Regulation, Developmental Histone Acetyltransferases - genetics Histone Acetyltransferases - metabolism Histone Deacetylases - genetics Histone Deacetylases - metabolism Histones - genetics Histones - metabolism Hydroxamic Acids - pharmacology Original Research Reports POU Domain Factors - genetics POU Domain Factors - metabolism Promoter Regions, Genetic Protein Processing, Post-Translational
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