A role for TLR signaling during B cell activation in antiretroviral-treated HIV individuals

The mechanisms underlying B cell activation that persists during antiretroviral therapy (ART) are unknown. Toll-like receptor (TLR) signaling is a critical mediator of innate cell activation and though B cells express TLRs, few studies have investigated a role for TLR signaling in B cell activation...

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Veröffentlicht in:	AIDS research and human retroviruses 2013-10, Vol.29 (10), p.1353-1360
Hauptverfasser:	Siewe, Basile, Keshavarzian, Ali, French, Audrey, Demarais, Patricia, Landay, Alan
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged AIDS/HIV Anti-Retroviral Agents - therapeutic use B-Lymphocytes - immunology Female Gene Expression Profiling HIV Infections - drug therapy HIV Infections - immunology Human immunodeficiency virus Humans Immunophenotyping Lymphocyte Activation Male Middle Aged Pathogenesis Retrovirus Signal Transduction Toll-Like Receptors - metabolism
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