Association of Ketone Body Levels With Hyperglycemia and Type 2 Diabetes in 9,398 Finnish Men

We investigated the association of the levels of ketone bodies (KBs) with hyperglycemia and with 62 genetic risk variants regulating glucose levels or type 2 diabetes in the population-based Metabolic Syndrome in Men (METSIM) study, including 9,398 Finnish men without diabetes or newly diagnosed typ...

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Veröffentlicht in:	Diabetes (New York, N.Y.) N.Y.), 2013-10, Vol.62 (10), p.3618-3626
Hauptverfasser:	MAHENDRAN, Yuvaraj, VANGIPURAPU, Jagadish, PAJUKANTA, Päivi, LUSIS, Aldons J, BONNYCASTLE, Lori L, MORKEN, Mario A, COLLINS, Francis S, MOHLKE, Karen L, BOEHNKE, Michael, ALA-KORPELA, Mika, KUUSISTO, Johanna, LAAKSO, Markku, CEDERBERG, Henna, STANCAKOVA, Alena, PIHLAJAMÄKI, Jussi, SOININEN, Pasi, KANGAS, Antti J, PAANANEN, Jussi, CIVELEK, Mete, SALEEM, Niyas K
Format:	Artikel
Sprache:	eng
Schlagworte:	3-Hydroxybutyric Acid - blood Acetoacetates - blood Area Under Curve Biological and medical sciences Biomarkers - blood Blood Glucose - metabolism Care and treatment Diabetes Diabetes Mellitus, Type 2 - blood Diabetes Mellitus, Type 2 - epidemiology Diabetes Mellitus, Type 2 - genetics Diabetes. Impaired glucose tolerance Endocrine pancreas. Apud cells (diseases) Endocrinopathies Etiopathogenesis. Screening. Investigations. Target tissue resistance European Continental Ancestry Group - genetics Fasting Finland - epidemiology Genetics Genome-Wide Association Study Glucose metabolism Glucose Tolerance Test Glucose tolerance tests Health aspects Humans Hyperglycemia Hyperglycemia - blood Hyperglycemia - epidemiology Hyperglycemia - genetics Insulin Ketone Bodies - blood Ketones Male Medical sciences Men Metabolic Syndrome - blood Metabolic Syndrome - epidemiology Middle Aged Organic chemicals Original Research Physiological aspects Polymorphism, Single Nucleotide Predictive Value of Tests Risk Factors Type 2 diabetes
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