α-Synuclein Senses Lipid Packing Defects and Induces Lateral Expansion of Lipids Leading to Membrane Remodeling

There is increasing evidence for the involvement of lipid membranes in both the functional and pathological properties of α-synuclein (α-Syn). Despite many investigations to characterize the binding of α-Syn to membranes, there is still a lack of understanding of the binding mode linking the propert...

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Veröffentlicht in:The Journal of biological chemistry 2013-07, Vol.288 (29), p.20883-20895
Hauptverfasser: Ouberai, Myriam M., Wang, Juan, Swann, Marcus J., Galvagnion, Celine, Guilliams, Tim, Dobson, Christopher M., Welland, Mark E.
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Sprache:eng
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