Predicting antimicrobial susceptibilities for Escherichia coli and Klebsiella pneumoniae isolates using whole genomic sequence data

Whole-genome sequencing potentially represents a single, rapid and cost-effective approach to defining resistance mechanisms and predicting phenotype, and strain type, for both clinical and epidemiological purposes. This retrospective study aimed to determine the efficacy of whole genome-based antim...

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Veröffentlicht in:	Journal of antimicrobial chemotherapy 2013-10, Vol.68 (10), p.2234-2244
Hauptverfasser:	Stoesser, N, Batty, E M, Eyre, D W, Morgan, M, Wyllie, D H, Del Ojo Elias, C, Johnson, J R, Walker, A S, Peto, T E A, Crook, D W
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - pharmacology Bacteremia - microbiology Chromosomes DNA, Bacterial - genetics Drug resistance Drug Resistance, Bacterial E coli Epidemiology Escherichia coli Escherichia coli - drug effects Escherichia coli - genetics Escherichia coli - isolation & purification Genome, Bacterial Genomics Genotype & phenotype Humans Klebsiella pneumoniae Klebsiella pneumoniae - drug effects Klebsiella pneumoniae - genetics Klebsiella pneumoniae - isolation & purification Microbial Sensitivity Tests - methods Mutation Original Research Sensitivity and Specificity Sequence Analysis, DNA United Kingdom
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