Hantavirus fever without pulmonary syndrome in Panama
In Panama, hantavirus pulmonary syndrome (HPS) is caused by Choclo virus, a species phylogenetically related to Andes and Maporal viruses. Up to 60% of the population has been positive for specific serum antibody in community-based surveys, but mortality is very uncommon. In four western Panama clin...
Gespeichert in:
| Veröffentlicht in: | The American journal of tropical medicine and hygiene 2013-09, Vol.89 (3), p.489-494 |
|---|---|
| Hauptverfasser: | , , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 494 |
|---|---|
| container_issue | 3 |
| container_start_page | 489 |
| container_title | The American journal of tropical medicine and hygiene |
| container_volume | 89 |
| creator | Armien, Blas Pascale, Juan M Muñoz, Carlos Mariñas, Jamileth Núñez, Heydy Herrera, Milagro Trujillo, José Sánchez, Deyanira Mendoza, Yaxelis Hjelle, Brian Koster, Frederick |
| description | In Panama, hantavirus pulmonary syndrome (HPS) is caused by Choclo virus, a species phylogenetically related to Andes and Maporal viruses. Up to 60% of the population has been positive for specific serum antibody in community-based surveys, but mortality is very uncommon. In four western Panama clinics, we tested individuals presenting with a severe febrile prodrome for acute hantavirus (HV) infection by immunoglobulin M enzyme-linked immunosorbent assay and reverse transcription polymerase chain reaction as well as clinically similar infections, such as dengue and leptospirosis. From 2006 to 2009, at least 21% of 117 patients diagnosed with HV infection had HV Fever (HF) with no evidence of pulmonary edema (no respiratory distress or radiographic lung infiltrates), and 44% of patients had very mild HPS (radiographic pulmonary edema but no respiratory insufficiency). HV infection caused by Choclo virus in Panama presents often as HF, which contrasts with HV in the Americas but is consistent with the high seroprevalence in endemic regions. |
| doi_str_mv | 10.4269/ajtmh.12-0334 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3771286</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1647001251</sourcerecordid><originalsourceid>FETCH-LOGICAL-c420t-406547bf845c17ee36f7bf08676b51f2bcb7a48f2ab1b52d54666106df8aff103</originalsourceid><addsrcrecordid>eNqFkc1Lw0AQxRdRbK0evUqOXlJ39rsXQYpaoaAHPS-bZNemJNm6m1T635vaWvTkaRjmx-PNewhdAh4zIiY3ZtnWizGQFFPKjtAQmBQpCMaP0RBjTNKJoHKAzmJcYgyKAJyiAaGKCi74EPGZaVqzLkMXE2fXNiSfZbvwXZusuqr2jQmbJG6aIvjaJmWTvJjG1OYcnThTRXuxnyP09nD_Op2l8-fHp-ndPM0ZwW3KsOBMZk4xnoO0lgrXb1gJKTIOjmR5Jg1TjpgMMk4KzoQQgEXhlHEOMB2h253uqstqW-S2aYOp9CqUdW9Me1Pqv5emXOh3v9ZUSiBK9ALXe4HgPzobW12XMbdVZRrru6j7oGQfC-HwP8oYpYozIns03aF58DEG6w6OAOttK_q7FQ1Eb1vp-avfbxzonxroF0OgiZE</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1443385427</pqid></control><display><type>article</type><title>Hantavirus fever without pulmonary syndrome in Panama</title><source>MEDLINE</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>PubMed Central</source><source>Alma/SFX Local Collection</source><creator>Armien, Blas ; Pascale, Juan M ; Muñoz, Carlos ; Mariñas, Jamileth ; Núñez, Heydy ; Herrera, Milagro ; Trujillo, José ; Sánchez, Deyanira ; Mendoza, Yaxelis ; Hjelle, Brian ; Koster, Frederick</creator><creatorcontrib>Armien, Blas ; Pascale, Juan M ; Muñoz, Carlos ; Mariñas, Jamileth ; Núñez, Heydy ; Herrera, Milagro ; Trujillo, José ; Sánchez, Deyanira ; Mendoza, Yaxelis ; Hjelle, Brian ; Koster, Frederick</creatorcontrib><description>In Panama, hantavirus pulmonary syndrome (HPS) is caused by Choclo virus, a species phylogenetically related to Andes and Maporal viruses. Up to 60% of the population has been positive for specific serum antibody in community-based surveys, but mortality is very uncommon. In four western Panama clinics, we tested individuals presenting with a severe febrile prodrome for acute hantavirus (HV) infection by immunoglobulin M enzyme-linked immunosorbent assay and reverse transcription polymerase chain reaction as well as clinically similar infections, such as dengue and leptospirosis. From 2006 to 2009, at least 21% of 117 patients diagnosed with HV infection had HV Fever (HF) with no evidence of pulmonary edema (no respiratory distress or radiographic lung infiltrates), and 44% of patients had very mild HPS (radiographic pulmonary edema but no respiratory insufficiency). HV infection caused by Choclo virus in Panama presents often as HF, which contrasts with HV in the Americas but is consistent with the high seroprevalence in endemic regions.</description><identifier>ISSN: 0002-9637</identifier><identifier>EISSN: 1476-1645</identifier><identifier>DOI: 10.4269/ajtmh.12-0334</identifier><identifier>PMID: 23836565</identifier><language>eng</language><publisher>United States: The American Society of Tropical Medicine and Hygiene</publisher><subject>Adolescent ; Adult ; Aged ; Antibodies, Viral - blood ; Child ; Child, Preschool ; Female ; Hantavirus ; Hantavirus - genetics ; Hantavirus - isolation & purification ; Hantavirus Pulmonary Syndrome - diagnosis ; Hantavirus Pulmonary Syndrome - epidemiology ; Hemorrhagic Fever with Renal Syndrome - diagnosis ; Hemorrhagic Fever with Renal Syndrome - epidemiology ; Humans ; Immunoglobulin M - blood ; Leptospira ; Male ; Middle Aged ; Panama - epidemiology ; RNA, Viral - isolation & purification ; Seroepidemiologic Studies ; Young Adult</subject><ispartof>The American journal of tropical medicine and hygiene, 2013-09, Vol.89 (3), p.489-494</ispartof><rights>The American Society of Tropical Medicine and Hygiene 2013</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c420t-406547bf845c17ee36f7bf08676b51f2bcb7a48f2ab1b52d54666106df8aff103</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3771286/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3771286/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,724,777,781,882,27905,27906,53772,53774</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23836565$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Armien, Blas</creatorcontrib><creatorcontrib>Pascale, Juan M</creatorcontrib><creatorcontrib>Muñoz, Carlos</creatorcontrib><creatorcontrib>Mariñas, Jamileth</creatorcontrib><creatorcontrib>Núñez, Heydy</creatorcontrib><creatorcontrib>Herrera, Milagro</creatorcontrib><creatorcontrib>Trujillo, José</creatorcontrib><creatorcontrib>Sánchez, Deyanira</creatorcontrib><creatorcontrib>Mendoza, Yaxelis</creatorcontrib><creatorcontrib>Hjelle, Brian</creatorcontrib><creatorcontrib>Koster, Frederick</creatorcontrib><title>Hantavirus fever without pulmonary syndrome in Panama</title><title>The American journal of tropical medicine and hygiene</title><addtitle>Am J Trop Med Hyg</addtitle><description>In Panama, hantavirus pulmonary syndrome (HPS) is caused by Choclo virus, a species phylogenetically related to Andes and Maporal viruses. Up to 60% of the population has been positive for specific serum antibody in community-based surveys, but mortality is very uncommon. In four western Panama clinics, we tested individuals presenting with a severe febrile prodrome for acute hantavirus (HV) infection by immunoglobulin M enzyme-linked immunosorbent assay and reverse transcription polymerase chain reaction as well as clinically similar infections, such as dengue and leptospirosis. From 2006 to 2009, at least 21% of 117 patients diagnosed with HV infection had HV Fever (HF) with no evidence of pulmonary edema (no respiratory distress or radiographic lung infiltrates), and 44% of patients had very mild HPS (radiographic pulmonary edema but no respiratory insufficiency). HV infection caused by Choclo virus in Panama presents often as HF, which contrasts with HV in the Americas but is consistent with the high seroprevalence in endemic regions.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Antibodies, Viral - blood</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Female</subject><subject>Hantavirus</subject><subject>Hantavirus - genetics</subject><subject>Hantavirus - isolation & purification</subject><subject>Hantavirus Pulmonary Syndrome - diagnosis</subject><subject>Hantavirus Pulmonary Syndrome - epidemiology</subject><subject>Hemorrhagic Fever with Renal Syndrome - diagnosis</subject><subject>Hemorrhagic Fever with Renal Syndrome - epidemiology</subject><subject>Humans</subject><subject>Immunoglobulin M - blood</subject><subject>Leptospira</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Panama - epidemiology</subject><subject>RNA, Viral - isolation & purification</subject><subject>Seroepidemiologic Studies</subject><subject>Young Adult</subject><issn>0002-9637</issn><issn>1476-1645</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkc1Lw0AQxRdRbK0evUqOXlJ39rsXQYpaoaAHPS-bZNemJNm6m1T635vaWvTkaRjmx-PNewhdAh4zIiY3ZtnWizGQFFPKjtAQmBQpCMaP0RBjTNKJoHKAzmJcYgyKAJyiAaGKCi74EPGZaVqzLkMXE2fXNiSfZbvwXZusuqr2jQmbJG6aIvjaJmWTvJjG1OYcnThTRXuxnyP09nD_Op2l8-fHp-ndPM0ZwW3KsOBMZk4xnoO0lgrXb1gJKTIOjmR5Jg1TjpgMMk4KzoQQgEXhlHEOMB2h253uqstqW-S2aYOp9CqUdW9Me1Pqv5emXOh3v9ZUSiBK9ALXe4HgPzobW12XMbdVZRrru6j7oGQfC-HwP8oYpYozIns03aF58DEG6w6OAOttK_q7FQ1Eb1vp-avfbxzonxroF0OgiZE</recordid><startdate>20130901</startdate><enddate>20130901</enddate><creator>Armien, Blas</creator><creator>Pascale, Juan M</creator><creator>Muñoz, Carlos</creator><creator>Mariñas, Jamileth</creator><creator>Núñez, Heydy</creator><creator>Herrera, Milagro</creator><creator>Trujillo, José</creator><creator>Sánchez, Deyanira</creator><creator>Mendoza, Yaxelis</creator><creator>Hjelle, Brian</creator><creator>Koster, Frederick</creator><general>The American Society of Tropical Medicine and Hygiene</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>7QL</scope><scope>7U9</scope><scope>C1K</scope><scope>F1W</scope><scope>H94</scope><scope>H95</scope><scope>H97</scope><scope>L.G</scope><scope>M7N</scope><scope>5PM</scope></search><sort><creationdate>20130901</creationdate><title>Hantavirus fever without pulmonary syndrome in Panama</title><author>Armien, Blas ; Pascale, Juan M ; Muñoz, Carlos ; Mariñas, Jamileth ; Núñez, Heydy ; Herrera, Milagro ; Trujillo, José ; Sánchez, Deyanira ; Mendoza, Yaxelis ; Hjelle, Brian ; Koster, Frederick</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c420t-406547bf845c17ee36f7bf08676b51f2bcb7a48f2ab1b52d54666106df8aff103</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Aged</topic><topic>Antibodies, Viral - blood</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Female</topic><topic>Hantavirus</topic><topic>Hantavirus - genetics</topic><topic>Hantavirus - isolation & purification</topic><topic>Hantavirus Pulmonary Syndrome - diagnosis</topic><topic>Hantavirus Pulmonary Syndrome - epidemiology</topic><topic>Hemorrhagic Fever with Renal Syndrome - diagnosis</topic><topic>Hemorrhagic Fever with Renal Syndrome - epidemiology</topic><topic>Humans</topic><topic>Immunoglobulin M - blood</topic><topic>Leptospira</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Panama - epidemiology</topic><topic>RNA, Viral - isolation & purification</topic><topic>Seroepidemiologic Studies</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Armien, Blas</creatorcontrib><creatorcontrib>Pascale, Juan M</creatorcontrib><creatorcontrib>Muñoz, Carlos</creatorcontrib><creatorcontrib>Mariñas, Jamileth</creatorcontrib><creatorcontrib>Núñez, Heydy</creatorcontrib><creatorcontrib>Herrera, Milagro</creatorcontrib><creatorcontrib>Trujillo, José</creatorcontrib><creatorcontrib>Sánchez, Deyanira</creatorcontrib><creatorcontrib>Mendoza, Yaxelis</creatorcontrib><creatorcontrib>Hjelle, Brian</creatorcontrib><creatorcontrib>Koster, Frederick</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Virology and AIDS Abstracts</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ASFA: Aquatic Sciences and Fisheries Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) 1: Biological Sciences & Living Resources</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) 3: Aquatic Pollution & Environmental Quality</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) Professional</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>The American journal of tropical medicine and hygiene</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Armien, Blas</au><au>Pascale, Juan M</au><au>Muñoz, Carlos</au><au>Mariñas, Jamileth</au><au>Núñez, Heydy</au><au>Herrera, Milagro</au><au>Trujillo, José</au><au>Sánchez, Deyanira</au><au>Mendoza, Yaxelis</au><au>Hjelle, Brian</au><au>Koster, Frederick</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Hantavirus fever without pulmonary syndrome in Panama</atitle><jtitle>The American journal of tropical medicine and hygiene</jtitle><addtitle>Am J Trop Med Hyg</addtitle><date>2013-09-01</date><risdate>2013</risdate><volume>89</volume><issue>3</issue><spage>489</spage><epage>494</epage><pages>489-494</pages><issn>0002-9637</issn><eissn>1476-1645</eissn><abstract>In Panama, hantavirus pulmonary syndrome (HPS) is caused by Choclo virus, a species phylogenetically related to Andes and Maporal viruses. Up to 60% of the population has been positive for specific serum antibody in community-based surveys, but mortality is very uncommon. In four western Panama clinics, we tested individuals presenting with a severe febrile prodrome for acute hantavirus (HV) infection by immunoglobulin M enzyme-linked immunosorbent assay and reverse transcription polymerase chain reaction as well as clinically similar infections, such as dengue and leptospirosis. From 2006 to 2009, at least 21% of 117 patients diagnosed with HV infection had HV Fever (HF) with no evidence of pulmonary edema (no respiratory distress or radiographic lung infiltrates), and 44% of patients had very mild HPS (radiographic pulmonary edema but no respiratory insufficiency). HV infection caused by Choclo virus in Panama presents often as HF, which contrasts with HV in the Americas but is consistent with the high seroprevalence in endemic regions.</abstract><cop>United States</cop><pub>The American Society of Tropical Medicine and Hygiene</pub><pmid>23836565</pmid><doi>10.4269/ajtmh.12-0334</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0002-9637 |
| ispartof | The American journal of tropical medicine and hygiene, 2013-09, Vol.89 (3), p.489-494 |
| issn | 0002-9637 1476-1645 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3771286 |
| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central; Alma/SFX Local Collection |
| subjects | Adolescent Adult Aged Antibodies, Viral - blood Child Child, Preschool Female Hantavirus Hantavirus - genetics Hantavirus - isolation & purification Hantavirus Pulmonary Syndrome - diagnosis Hantavirus Pulmonary Syndrome - epidemiology Hemorrhagic Fever with Renal Syndrome - diagnosis Hemorrhagic Fever with Renal Syndrome - epidemiology Humans Immunoglobulin M - blood Leptospira Male Middle Aged Panama - epidemiology RNA, Viral - isolation & purification Seroepidemiologic Studies Young Adult |
| title | Hantavirus fever without pulmonary syndrome in Panama |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-19T17%3A10%3A23IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Hantavirus%20fever%20without%20pulmonary%20syndrome%20in%20Panama&rft.jtitle=The%20American%20journal%20of%20tropical%20medicine%20and%20hygiene&rft.au=Armien,%20Blas&rft.date=2013-09-01&rft.volume=89&rft.issue=3&rft.spage=489&rft.epage=494&rft.pages=489-494&rft.issn=0002-9637&rft.eissn=1476-1645&rft_id=info:doi/10.4269/ajtmh.12-0334&rft_dat=%3Cproquest_pubme%3E1647001251%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1443385427&rft_id=info:pmid/23836565&rfr_iscdi=true |